First do no harm: valproate and medicines safety in pregnancy.
作者信息
Robson John, Moss Ngawai, McGettigan Patricia, Beardsley Samantha Jane, Lovegrove Elizabeth, Dezateux Carol
机构信息
Institute of Population Health Sciences, Queen Mary University of London, London.
William Harvey Research Institute, Queen Mary University of London, London.
出版信息
Br J Gen Pract. 2020 Oct 1;70(699):477-478. doi: 10.3399/bjgp20X712673. Print 2020 Oct.
Abstract
摘要
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First do no harm: valproate and medicines safety in pregnancy.首要原则是不伤害：丙戊酸盐与孕期用药安全
Br J Gen Pract. 2020 Oct 1;70(699):477-478. doi: 10.3399/bjgp20X712673. Print 2020 Oct.
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Dangers of valproate in pregnancy.丙戊酸盐在孕期的风险
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Women still not being told about pregnancy risks of valproate.女性仍未被告知丙戊酸盐的妊娠风险。
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Valproate and pregnancy: think again.丙戊酸盐与妊娠：再思考一下。
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Valproate use during pregnancy was linked to autism spectrum disorder and childhood autism in offspring.孕期使用丙戊酸盐与后代患自闭症谱系障碍和儿童自闭症有关。
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[Fetal valproate syndrome].[胎儿丙戊酸盐综合征]
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Weighing the risks of valproate in women who could become pregnant.权衡丙戊酸盐对可能怀孕女性的风险。
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Risks of in utero exposure to valproate.子宫内接触丙戊酸盐的风险。
JAMA. 2013 Apr 24;309(16):1730-1. doi: 10.1001/jama.2013.4001.
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[Caution and warning: About valproate and pregnancy].[注意事项及警告：关于丙戊酸盐与妊娠]
Encephale. 2016 Oct;42(5):391-394. doi: 10.1016/j.encep.2016.10.005.
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Valproate in pregnancy linked to autism in children.孕期使用丙戊酸盐与儿童自闭症有关。
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Valproate use in women aged 15-44 years: an observational study in general practice.15至44岁女性使用丙戊酸盐：一项全科医疗中的观察性研究
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本文引用的文献
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Pregnancy protection and pregnancies in women prescribed ACE inhibitors or ARBs: a cross-sectional study in primary care.在基层医疗中，使用 ACEI 或 ARB 类药物的女性妊娠保护和妊娠情况：一项横断面研究。
Br J Gen Pract. 2020 Oct 29;70(700):e778-e784. doi: 10.3399/bjgp20X712997. Print 2020 Nov.
2
Risk of early neurodevelopmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: a French nationwide population-based cohort study.与妊娠期间最常使用的抗癫痫药物相关的产前暴露的早期神经发育结局风险：一项法国全国基于人群的队列研究。
BMJ Open. 2020 Jun 7;10(6):e034829. doi: 10.1136/bmjopen-2019-034829.
3
Sodium valproate in pregnancy: what are the risks and should we use a shared decision-making approach?孕期使用丙戊酸钠：风险有哪些？我们是否应该采用共同决策方法？
BMC Pregnancy Childbirth. 2018 Jun 1;18(1):200. doi: 10.1186/s12884-018-1842-x.
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AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies.妊娠抗癫痫药物监测（EMPiRE）：监测策略有效性和可接受性的双盲随机试验。
Health Technol Assess. 2018 May;22(23):1-152. doi: 10.3310/hta22230.
5
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.八款不同抗癫痫药物致主要先天畸形的比较风险：EURAP 注册前瞻性队列研究。
Lancet Neurol. 2018 Jun;17(6):530-538. doi: 10.1016/S1474-4422(18)30107-8. Epub 2018 Apr 18.
6
A UK clinical audit addressing the quality of prescribing of sodium valproate for bipolar disorder in women of childbearing age.一项针对育龄期女性双相情感障碍患者丙戊酸钠处方质量的英国临床审计。
BMJ Open. 2018 Apr 12;8(4):e020450. doi: 10.1136/bmjopen-2017-020450.
7
Major congenital malformations after first-trimester exposure to ACE inhibitors.孕早期接触血管紧张素转换酶抑制剂后出现的严重先天性畸形。
N Engl J Med. 2006 Jun 8;354(23):2443-51. doi: 10.1056/NEJMoa055202.
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