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根据年龄分组对急性心肌梗死进行的临床研究。

Clinical investigation of acute myocardial infarction according to age subsets.

作者信息

Wang Jianwei, Li Li, Ma Ning, Zhang Xiaohui, Qiao Yanyan, Fang Guangjie, Li Guoping, Zhong Tao

机构信息

ECG Room, Weifang Maternal and Child Health Hospital, Weifang, Shandong 261000, P.R. China.

ECG Room, Qianfoshan Hospital Affiliated to Shandong University, Jinan, Shandong 250014, P.R. China.

出版信息

Exp Ther Med. 2020 Nov;20(5):120. doi: 10.3892/etm.2020.9248. Epub 2020 Sep 21.

DOI:10.3892/etm.2020.9248
PMID:33005246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7523297/
Abstract

A growing number of 'Young' patients less than 40 years of age are being hospitalized with a diagnosis of acute myocardial infarction (AMI) due to increased prevalence of risk factors for atherosclerosis. The aim of this study was to compare clinical characteristics and performances of AMI between young and elderly patients. We conducted a retrospective study to compare AMI in young patients and elder patients. Based on the medical record databases in our hospital, we enrolled 114 'young' AMI patients (age ≤42 years) and 179 'elder' AMI patients (≥60 years), and then collected and analyzed their demographic information, clinical performances, and coronary angiography results. In the young AMI group, the proportion of male patients was higher than that in the elder AMI group (94.7 vs. 64.2%, P<0.05). Compared with the elder AMI patients, young patients had higher rates of smoking history and positive family medical history, but lower rates of hypertension and diabetes. Elder patients with AMI were more likely to develop various clinical performances, and multiple-branch lesions; however, young AMI patients had relatively fewer symptoms, and the tissue lesions were more limited. The clinical profiles of AMI in young patients were different from that in elder AMI patients. Specific interventions should be carried out to prevent and control the prevalence of AMI in the young population.

摘要

由于动脉粥样硬化危险因素的患病率增加,越来越多40岁以下的“年轻”患者因急性心肌梗死(AMI)住院。本研究的目的是比较年轻和老年AMI患者的临床特征和表现。我们进行了一项回顾性研究,以比较年轻患者和老年患者的AMI情况。基于我院的病历数据库,我们纳入了114例“年轻”AMI患者(年龄≤42岁)和179例“老年”AMI患者(≥60岁),然后收集并分析了他们的人口统计学信息、临床表现和冠状动脉造影结果。在年轻AMI组中,男性患者的比例高于老年AMI组(94.7%对64.2%,P<0.05)。与老年AMI患者相比,年轻患者有吸烟史和家族病史阳性的比例更高,但高血压和糖尿病的比例更低。老年AMI患者更容易出现各种临床表现和多支病变;然而,年轻AMI患者的症状相对较少,组织病变也更局限。年轻患者AMI的临床特征与老年AMI患者不同。应采取具体干预措施来预防和控制年轻人群中AMI的患病率。

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本文引用的文献

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Trends in rate of acute myocardial infarction among patients aged <30 years.30岁以下患者急性心肌梗死发生率的趋势。
Nat Rev Cardiol. 2018 Feb;15(2):119. doi: 10.1038/nrcardio.2017.191. Epub 2017 Dec 14.
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Clinical characteristics and prognosis of acute myocardial infarction in young smokers and non-smokers (≤ 45 years): a systematic review and meta-analysis.年轻吸烟者和非吸烟者(≤45岁)急性心肌梗死的临床特征与预后:一项系统评价和荟萃分析
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Zhonghua Xin Xue Guan Bing Za Zhi. 2017 Feb 24;45(2):154-159. doi: 10.3760/cma.j.issn.0253-3758.2017.02.016.
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Differing Clinical Characteristics Between Young and Older Patients Presenting with Myocardial Infarction.年轻与老年心肌梗死患者的不同临床特征
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