Nlandu Yannick M, Makulo Jean-Robert R, Pakasa Nestor M, Sumaili Ernest K, Nkondi Clarisse N, Bukabau Justine B, Beya François K, Nseka Nazaire M, Lepira François B
Kinshasa University Hospital, Nephrology Unit, Kinshasa, Democratic Republic of the Congo.
Division of Uro-Nephropathology, Department of Pathology, Kinshasa, Democratic Republic of the Congo.
Case Rep Nephrol. 2020 Sep 28;2020:8820713. doi: 10.1155/2020/8820713. eCollection 2020.
Although the lungs remain the main target of SARS-CoV-2, other organs, such as kidneys, can be affected, which has a negative impact on the outcomes of COVID-19 patients. Although previous studies of kidney disease in COVID-19 reported mainly SARS-CoV-2-induced tubular and interstitial injury, there is growing evidence coming out of Africa of glomerular involvement, especially collapsing glomerulopathy seen particularly in people of African descent. We report a case of collapsing glomerulopathy revealed by acute kidney injury and a new onset of full blown nephrotic syndrome in a black Congolese patient coinfected with COVID-19 and malaria.
尽管肺部仍是SARS-CoV-2的主要靶器官，但肾脏等其他器官也可能受到影响，这对COVID-19患者的预后产生负面影响。尽管先前关于COVID-19患者肾脏疾病的研究主要报道了SARS-CoV-2引起的肾小管和间质损伤，但非洲越来越多的证据表明存在肾小球受累情况，尤其是在非洲裔人群中特别常见的塌陷性肾小球病。我们报告了1例刚果黑人患者，该患者同时感染了COVID-19和疟疾，因急性肾损伤和新发的全面肾病综合征而被诊断为塌陷性肾小球病。
