Sreebny L M, Valdini A
Arch Intern Med. 1987 Jul;147(7):1333-7. doi: 10.1001/archinte.147.7.1333.
Xerostomia, the subjective feeling of dry mouth caused by a severe reduction in the flow of saliva, is a common problem that is particularly prevalent among the aged. It has become increasingly evident that dry mouth is associated with a number of serious systemic conditions and diseases. Among these are the intake of commonly prescribed medications, autoimmune diseases, and irradiation to the head and neck. The diminution in the flow of saliva may profoundly affect oral health, disturb digestion and speech, and seriously impair the patient's quality of life. Food avoidance, nonabsorption of sublingually placed drugs, and noncompliance with medication may also result. Sialometry can be used to confirm the presence of dry mouth. Treatment is aimed at increasing the flow of saliva, when possible, or providing oral moisture by other means.
口干症是指由于唾液分泌严重减少而引起的口腔主观干燥感,是一个常见问题,在老年人中尤为普遍。越来越明显的是,口干与许多严重的全身性疾病有关。其中包括常用处方药的摄入、自身免疫性疾病以及头颈部放疗。唾液分泌减少可能会严重影响口腔健康、扰乱消化和言语功能,并严重损害患者的生活质量。还可能导致患者避免进食、舌下含服药物不吸收以及不遵医嘱服药。唾液流量测定可用于确认是否存在口干症。治疗旨在尽可能增加唾液分泌,或通过其他方式提供口腔湿润。