Lindvall Olle
Laboratory of Stem Cells and Restorative Neurology, Lund Stem Cell Center, Lund University, SE-221 84 Lund, Sweden.
Cell Stem Cell. 2020 Oct 1;27(4):519-522. doi: 10.1016/j.stem.2020.09.002.
Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson's disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.
即将开展的评估将干细胞衍生的多巴胺能神经元移植到帕金森病患者纹状体中的临床试验，可能会在人类大脑神经元替代方面产生开创性的成果。然而，如此处所强调的，要找到一种针对这种多系统疾病具有临床竞争力的治疗方法，可能还有很长的路要走，且充满曲折。
