D'Angeli Giacomo, Messineo Daniela, Riminucci Mara, Corsi Alessandro, Celli Mauro, Vozza Iole, Sfasciotti Gian Luca
Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Department of Radiological, Oncology and Anatomo-Pathological Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Healthcare (Basel). 2020 Sep 30;8(4):372. doi: 10.3390/healthcare8040372.
(1) Objectives: The aim of our study was to investigate the anatomical features of lower third molar and its adjacent anatomical connections in type I Osteogenesis Imperfecta (OI) patients through cone beam computed tomography (cbct). (2) Methods: The study was conducted among 25 patients, 13 patients with type I OI and 12 control patients (individuals with no disorders and no treatment); average age was 15.44 ± 2.06, 23 third molar germs for each group. The germs have been compared to the parameters using the Mann-Whitney test. A chi-square test was also used to investigate the correlation between the status case/control and tooth development stage. (3) Results: Mann-Whitney test showed significant differences between cases and controls: diameter of the tooth germ in toto (U = 93.5; < 0.001), tooth development stage, (U = 145; < 0.01), roots length (U = 44.5; < 0.01), cementoenamel junction diameter (U = 157.5; < 0.05), size of the pulp chamber (U = 95.5; < 0.05). Type I OI is not associated with the relationship between the germ of mandibular third molar and alveolar canal on axial plane (χ = 4.095; = 0.129), and parasagittal (χ = 4.800; = 0.091). The association between type I OI and relationship with the germ of mandibular third molar and alveolar canal on the coronal plane has been significant (χ = 9.778; < 0.05) as the perforation of the lingual cortical bone in the region of mandibular third molar tooth germ (χ = 11.189; < 0.01). (4) Conclusions: The results confirm the cbct accuracy in the evaluation of bone density in type I OI patients giving also the opportunity to study the tridimensional anatomy of germs and the adjacent anatomical structures in order to avoid any perioperative complications.
(1) 目的：本研究旨在通过锥形束计算机断层扫描（CBCT）研究Ⅰ型成骨不全（OI）患者下颌第三磨牙的解剖特征及其相邻的解剖连接。(2) 方法：该研究在25例患者中进行，其中13例为Ⅰ型OI患者，12例为对照患者（无疾病且未接受治疗的个体）；平均年龄为15.44±2.06岁，每组有23个第三磨牙牙胚。使用曼-惠特尼检验将牙胚与各项参数进行比较。还使用卡方检验来研究病例/对照状态与牙齿发育阶段之间的相关性。(3) 结果：曼-惠特尼检验显示病例组与对照组之间存在显著差异：牙胚总体直径（U = 93.5；P < 0.001）、牙齿发育阶段（U = 145；P < 0.01）、牙根长度（U = 44.5；P < 0.01）、牙骨质釉质界直径（U = 157.5；P < 0.05）、牙髓腔大小（U = 95.5；P < 0.05）。Ⅰ型OI与下颌第三磨牙牙胚与牙槽管在轴平面上的关系无关（χ = 4.095；P = 0.129），在矢状旁平面上也无关（χ = 4.800；P = 0.091）。Ⅰ型OI与下颌第三磨牙牙胚与牙槽管在冠状平面上的关系具有显著相关性（χ = 9.778；P < 0.05），如下颌第三磨牙牙胚区域舌侧皮质骨穿孔（χ = 11.189；P < 0.01）。(4) 结论：结果证实了CBCT在评估Ⅰ型OI患者骨密度方面的准确性，同时也为研究牙胚及其相邻解剖结构的三维解剖提供了机会，以避免任何围手术期并发症。
