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小儿外科学中的阿片类药物管理:追求零。

Opioid stewardship in pediatric surgery: Approaching zero.

机构信息

University of Rochester School of Medicine and Dentistry, Rochester, NY.

Surgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD.

出版信息

J Pediatr Surg. 2021 Mar;56(3):573-579. doi: 10.1016/j.jpedsurg.2020.08.035. Epub 2020 Sep 9.

Abstract

INTRODUCTION

In response to the opioid epidemic, we hypothesized that adequate pain control can be achieved with few, if any, opioid prescriptions at discharge following pediatric surgical procedures.

METHODS

All records for patients 0-15 years old who underwent pediatric surgical operations from December 2017 through May 2018 were reviewed. Opioids prescriptions, emergency department (ED) visits, and hospital readmissions were recorded. Postoperative pain was assessed on a scale from 0 to 10 via phone call within three days of discharge.

RESULTS

352 patients underwent 394 surgical procedures. Three patients were prescribed opioids at discharge. There were no pain-related readmissions. One patient returned to the ED owing to pain. 116 unique pain scores were obtained from 114 patients: score 0 (n = 69, 59%), 1-3 (n = 31, 27%), 4-5 (n = 11, 9%), 6-8 (n = 5, 4%), and 9-10 (n = 0, 0%). There was a positive association between pain and increasing age (r = 0.26, p = 0.005). No patients who underwent hernia repair reported a pain score greater than 3.

CONCLUSIONS

Adequate pain control at discharge after pediatric general surgical procedures can be achieved for most children with scheduled nonopioid medications only. A limited supply of opioids for analgesia after discharge may benefit small subset of patients. This strategy would help reduce opioid prevalence in the community.

TYPE OF STUDY

Retrospective cohort study.

LEVEL OF EVIDENCE

Level III.

摘要

引言

针对阿片类药物流行,我们假设在小儿外科手术后出院时,如果使用少量(如果有的话)阿片类药物即可达到充分的疼痛控制。

方法

回顾了 2017 年 12 月至 2018 年 5 月期间接受小儿外科手术的 0-15 岁患者的所有记录。记录了阿片类药物处方、急诊(ED)就诊和住院再入院情况。在出院后三天内通过电话评估术后疼痛程度,范围从 0 到 10。

结果

352 名患者接受了 394 次手术。有 3 名患者在出院时开了阿片类药物。没有与疼痛相关的再入院。有 1 名患者因疼痛返回 ED。从 114 名患者中获得了 116 个独特的疼痛评分:0 分(n=69,59%),1-3 分(n=31,27%),4-5 分(n=11,9%),6-8 分(n=5,4%),和 9-10 分(n=0,0%)。疼痛与年龄增长呈正相关(r=0.26,p=0.005)。接受疝修补术的患者没有报告疼痛评分大于 3。

结论

对于大多数接受计划非阿片类药物治疗的小儿普通外科手术患者,在出院时即可达到充分的疼痛控制,仅使用有限的阿片类药物即可缓解疼痛。这种策略可能对一小部分患者有益,并有助于减少社区中阿片类药物的使用。

研究类型

回顾性队列研究。

证据等级

III 级。

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