牛巴氏杆菌的血清敏感性。
Serum susceptibility of bovine pasteurellas.
作者信息
Blau K A, Ward A C, Prieur D J, Corbeil L B
出版信息
Can J Vet Res. 1987 Apr;51(2):157-61.
Abstract
In this study, the serum sensitivity of 23 P. haemolytica isolates and 18 P. multocida isolates was determined by incubating dilutions of bacteria with equal volumes of fresh or heat-inactivated bovine serum for one, two, or three hours. Clinical isolates of both Pasteurella species were resistant to serum, whereas isolates from asymptomatic cattle varied in serum susceptibility. The classical pathway of complement appeared to be the principal means of complement mediated killing as detected by incubation in the presence or absence of EGTA-MgCl2. Lyzozyme and iron saturation of serum did not greatly affect serum susceptibility with either of the Pasteurella species.
摘要
在本研究中，通过将细菌稀释液与等体积的新鲜或热灭活牛血清孵育1、2或3小时，测定了23株溶血巴氏杆菌分离株和18株多杀巴氏杆菌分离株的血清敏感性。两种巴氏杆菌的临床分离株均对血清耐药，而来自无症状牛的分离株在血清敏感性上存在差异。补体的经典途径似乎是补体介导杀伤的主要方式，这通过在有或没有EGTA-MgCl2的情况下孵育来检测。溶菌酶和血清的铁饱和度对两种巴氏杆菌的血清敏感性影响不大。
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