晚期霍奇金病后慢性粒细胞白血病髓系原始细胞危象经化疗及随后的异基因骨髓移植治疗成功。
Successful treatment with chemotherapy and subsequent allogeneic bone marrow transplantation for myeloid blastic crisis of chronic myelogenous leukemia following advanced Hodgkin's disease.
作者信息
Punt C J, Rozenberg-Arska M, Verdonck L F
出版信息
Cancer. 1987 Sep 1;60(5):934-5. doi: 10.1002/1097-0142(19870901)60:5<934::aid-cncr2820600503>3.0.co;2-y.
A 33-year-old man was treated with intensive chemotherapy for myeloid blastic crisis of chronic myelogenous leukemia (CML), which developed after radiotherapy and chemotherapy for Hodgkin's disease. After achieving a second chronic phase, he underwent allogeneic bone marrow transplantation (BMT). Despite many complications, 1 year after BMT the disease was in complete remission and the patient was in excellent condition. The incidence of CML following treatment for Hodgkin's disease is briefly discussed. This is the first report of prolonged complete remission for blastic crisis of CML, which developed after combined treatment for advanced Hodgkin's disease.
一名33岁男性因慢性粒细胞白血病（CML）的髓系原始细胞危象接受了强化化疗，该危象发生在霍奇金病放疗和化疗之后。在进入第二次慢性期后，他接受了异基因骨髓移植（BMT）。尽管出现了许多并发症，但骨髓移植1年后疾病完全缓解，患者状况良好。本文简要讨论了霍奇金病治疗后发生CML的发生率。这是第一例关于晚期霍奇金病联合治疗后发生的CML原始细胞危象长期完全缓解的报告。
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