Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China; Shanghai Medical College, Fudan University, Shanghai, China.
Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
World Neurosurg. 2021 Feb;146:e22-e29. doi: 10.1016/j.wneu.2020.09.143. Epub 2020 Oct 1.
We searched PubMed, Embase, and the Cochrane Library for randomized controlled trials from January 1980 to April 2018 for adolescents with mild traumatic brain injury (mTBI) to explore the value of aerobic exercise in sport-related concussion (SRC) and mTBI treatment.
A meta-analysis for the postconcussion symptom scale (PCSS) score and time to recovery was performed with STATA software.
We found that aerobic exercise versus usual treatment significantly decreased the PCSS score (weighted mean difference = 6.51, 95% confidence interval: 0.29, 12.72; P = 0.040), as well as the time to recovery (weighted mean difference = -3.87; 95% confidence interval: -6.50, -1.23; P = 0.004). However, aerobic exercise showed no significant improvement in immediate postconcussion assessment and cognitive testing (P = 0.471/0.129/0.648/0.800, respectively, in verbal memory, visual memory, visual motor speed, and reaction time).
Compared with usual treatment, aerobic exercise promoted mTBI adolescents' recovery, assessed by PCSS and time to recovery. However, aerobic exercise may not help with neurocognitive function recovery.
我们检索了 PubMed、Embase 和 Cochrane 图书馆从 1980 年 1 月到 2018 年 4 月间有关青少年轻度创伤性脑损伤（mTBI）的随机对照试验，旨在探讨有氧运动在运动相关脑震荡（SRC）和 mTBI 治疗中的价值。
使用 STATA 软件对 postconcussion symptom scale（PCSS）评分和恢复时间进行荟萃分析。
我们发现，与常规治疗相比，有氧运动显著降低了 PCSS 评分（加权均数差=6.51，95%置信区间：0.29，12.72；P=0.040）和恢复时间（加权均数差=-3.87；95%置信区间：-6.50，-1.23；P=0.004）。然而，有氧运动在即时脑震荡评估和认知测试中并没有显著改善（分别在言语记忆、视觉记忆、视觉运动速度和反应时间方面的 P 值为 0.471/0.129/0.648/0.800）。
与常规治疗相比，有氧运动促进了 mTBI 青少年的恢复，通过 PCSS 和恢复时间进行评估。然而，有氧运动可能对神经认知功能的恢复没有帮助。
