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一项关于抗阻训练对血糖和妊娠结局影响的荟萃分析。

A meta-analysis of the effects of resistance training on blood sugar and pregnancy outcomes.

机构信息

The School of Nursing, Fujian Medical University, Fuzhou, Fujian Province, China; Clinical Nursing Teaching and Research department, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.

Clinical Nursing Teaching and Research department, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China.

出版信息

Midwifery. 2020 Dec;91:102839. doi: 10.1016/j.midw.2020.102839. Epub 2020 Sep 11.

DOI:10.1016/j.midw.2020.102839
PMID:33010591
Abstract

PROBLEM

There are different conclusions about the effects of resistance training on blood sugar levels and pregnancy outcomes in gestational diabetes mellitus (GDM) patients.

BACKGROUND

Resistance training is recommended as an easier and more practical method to exercise for women with GDM due to their growing belly. Although some researchers have explored this notion, there are no consistent conclusions about its effects.

AIM

To explore whether resistance training has an effect on blood sugar levels and pregnancy outcomes in patients with GDM in randomized controlled trials.

METHOD

Pubmed, Cochrane Library, CINAHL, Embase, Scopus, Web of Science, Clinical Trials, CKNI, Wanfang Database, VIP Database, and Chinese Biomedical Literature Database were systematically searched since their establishment to April 2019. Relevant meta-analyses, reviews, and eligible literature were also searched. The quality of the included literature was evaluated according to the Cochrane Assessment Manual 5.1.0. Meta-analysis was performed using Revman 5.3 software.

FINDINGS

A total of four studies (n = 242 patients) were included. Compared to the control group, there were statistical differences in fasting blood glucose level [MD=-0.37, 95%CI=(-0.65, -0.09), Z = 2.62, P = 0.009], average 2-h post-meal blood glucose level [MD=-0.96, 95%CI=(-1.80, -0.12), Z = 2.25, P = 0.02], insulin dosage [MD=-0.58, 95%CI=(-0.99, -0.17), Z = 2.75, P = 0.006], rate of insulin injection [RR=0.52, 95%CI=(0.31, 0.86), Z = 2.54, P = 0.01], and incidence of macrosomia [RR=0.15, 95%CI=(0.04,0.66), Z = 2.53, P = 0.01] in the intervention group consisting of GDM patients. There were no statistical differences in preterm delivery outcomes [RR=0.44, 95%CI=(0.09, 2.16), Z = 1.01, P = 0.31].

CONCLUSION

Resistance training can improve blood sugar levels, insulin usage, and some adverse pregnancy outcomes in patients with GDM and is therefore worthy of clinical promotion.

摘要

问题

对于妊娠期糖尿病(GDM)患者,抗阻训练对血糖水平和妊娠结局的影响存在不同结论。

背景

由于腹部增大,抗阻训练被推荐为 GDM 女性更简单、更实用的运动方式。尽管一些研究人员对此进行了探索,但对于其效果并没有一致的结论。

目的

在随机对照试验中探讨抗阻训练对 GDM 患者血糖水平和妊娠结局的影响。

方法

系统检索建库至 2019 年 4 月的 PubMed、Cochrane 图书馆、CINAHL、Embase、Scopus、Web of Science、ClinicalTrials、中国生物医学文献数据库、中国知网、维普数据库和万方数据库,同时检索相关的荟萃分析、综述和合格文献。根据 Cochrane 评估手册 5.1.0 评价纳入文献的质量。采用 Revman 5.3 软件进行荟萃分析。

结果

共纳入 4 项研究(n=242 例患者)。与对照组相比,干预组空腹血糖水平[MD=-0.37,95%CI=(-0.65,-0.09)],平均餐后 2 小时血糖水平[MD=-0.96,95%CI=(-1.80,-0.12)],胰岛素用量[MD=-0.58,95%CI=(-0.99,-0.17)],胰岛素注射率[RR=0.52,95%CI=(0.31,0.86)],巨大儿发生率[RR=0.15,95%CI=(0.04,0.66)]差异均有统计学意义。两组早产结局[RR=0.44,95%CI=(0.09,2.16)]差异无统计学意义。

结论

抗阻训练可改善 GDM 患者的血糖水平、胰岛素使用情况和部分不良妊娠结局,值得临床推广。

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