Department of Veterinary Preventive Medicine, The Ohio State University, Columbus 43210.
Department of Animal Sciences, The Ohio State University, Columbus 43210.
J Dairy Sci. 2020 Dec;103(12):11697-11712. doi: 10.3168/jds.2020-18388. Epub 2020 Oct 1.
Parturition is a natural process that gradually progresses from one stage to the next. However, around 5% of dairy cows will experience dystocia, which is considered to be a painful and stressful event. Studies have reported positive effects on cow performance and welfare after treatment with nonsteroidal anti-inflammatory drugs during the first postpartum days. The objectives were to assess the effects of acetylsalicylic acid administration after calving on (1) milk yield and components, (2) daily activity patterns, (3) reproductive performance, and (4) health in lactating dairy cows under certified organic management. Cows from 3 organic herds were enrolled. Within 12 h after parturition, cows were blocked by parity and calving ease and randomly assigned to 2 treatments: (1) aspirin (ASP; n = 278), in which cows received 4 consecutive treatments every 12 h with acetylsalicylic acid (100 mg/kg; 2 boluses) or (2) placebo (PLC, n = 285), in which cows received 4 treatments every 12 h with gelatin capsules (2 capsules) filled with water. Daily milk yield for the first 30 d in milk (DIM) and monthly milk yield, fat, protein, and somatic cell count (SCC) data from the first 5 Dairy Herd Improvement Association tests were collected. Activity patterns were measured using activity data loggers in the first 7 DIM. Clinical disease events (60 DIM) and fertility data were collected from on-farm computer records. Statistical analysis was performed using the MIXED (milk yield, components, and activity), LIFETEST (fertility), and GLIMMIX (health) procedures of SAS (SAS Institute Inc., Cary, NC). Overall, ASP cows produced 1.82 kg/d more milk than PLC cows during the first 30 DIM. Interestingly, cows that experienced dystocia and received ASP produced 4.48 kg/d more milk compared with cows in the PLC group that experienced dystocia. Cows treated with ASP had lower somatic cell count during the first 5 Dairy Herd Improvement Association tests. There were no differences in daily lying time, lying bouts, and lying bout duration between the ASP and PLC groups. However, cows in the ASP group had 587,64 steps/d more compared with PLC cows. In addition, ASP cows tended to require fewer days (ASP = 113.76 ± 4.99 d; PLC = 125.36 ± 4.74 d) and needed fewer services (ASP = 1.86 ± 0.21 services; PLC = 2.19 ± 0.24 services) to become pregnant compared with PLC cows. There were no differences in clinical disease events between treatments. Results from this study suggest that treating cows with ASP after calving may help improve milk yields and udder health, increase activity, and enhance fertility in dairy cattle under certified organic management.
分娩是一个渐进的自然过程，逐渐从一个阶段进展到另一个阶段。然而，大约 5%的奶牛会经历难产，这被认为是一种痛苦和有压力的事件。研究报告称，在产后头几天使用非甾体抗炎药治疗对奶牛的性能和福利有积极影响。本研究的目的是评估在产后立即给予乙酰水杨酸对（1）产奶量和成分、（2）每日活动模式、（3）繁殖性能和（4）泌乳奶牛健康的影响，这些奶牛是在经过认证的有机管理下饲养的。将来自 3 个有机牛群的奶牛纳入研究。产后 12 小时内，根据胎次和产犊难易程度将奶牛分组，并随机分为 2 个处理组：（1）阿司匹林（ASP；n = 278），每隔 12 小时连续给奶牛服用 4 次乙酰水杨酸（100mg/kg；2 个剂量），或（2）安慰剂（PLC；n = 285），每隔 12 小时给奶牛服用 4 次明胶胶囊（2 个胶囊），胶囊内装满水。收集产后第 1 天至第 30 天（DIM）的日产奶量和每月奶量、脂肪、蛋白质和体细胞计数（SCC）数据，第 5 次奶样的 Dairy Herd Improvement Association 测试数据。在产后第 1 天至第 7 天期间，使用活动数据记录仪测量活动模式。从农场计算机记录中收集临床疾病事件（60DIM）和繁殖数据。使用 SAS（SAS Institute Inc.，Cary，NC）的 MIXED（产奶量、成分和活动）、LIFETEST（繁殖）和 GLIMMIX（健康）程序进行统计分析。总体而言，在产后第 1 天至第 30 天期间，接受 ASP 治疗的奶牛比接受 PLC 治疗的奶牛多产奶 1.82kg/d。有趣的是，与接受 PLC 治疗的经历难产的奶牛相比，接受 ASP 治疗的经历难产的奶牛多产奶 4.48kg/d。接受 ASP 治疗的奶牛在前 5 次 Dairy Herd Improvement Association 测试中体细胞计数较低。ASP 和 PLC 组之间的每日躺卧时间、躺卧时间和躺卧持续时间没有差异。然而，与 PLC 组相比，ASP 组的奶牛每天多走 587,64 步/d。此外，ASP 组的奶牛需要的天数（ASP = 113.76 ± 4.99d；PLC = 125.36 ± 4.74d）和配种服务次数（ASP = 1.86 ± 0.21 次；PLC = 2.19 ± 0.24 次）均少于 PLC 组。两种处理组之间的临床疾病事件没有差异。本研究结果表明，在产后立即给奶牛使用 ASP 可能有助于提高产奶量和乳房健康，增加奶牛的活动量，提高有机管理下奶牛的繁殖力。
