Department of Thoracic Surgery, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1023, New York, NY 10029, USA.
Department of Thoracic Surgery, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1023, New York, NY 10029, USA.
Thorac Surg Clin. 2020 Nov;30(4):481-487. doi: 10.1016/j.thorsurg.2020.08.002.
Malignant pleural mesothelioma is an aggressive, deadly cancer often requiring input from multiple medical disciplines. Treatment has evolved over the last several decades with increasing evidence and ongoing advances in chemotherapy, radiation, and immunotherapy; however, no standard treatment regimen has yet been defined. Regardless of the overall strategy, surgery remains the foundation of treatment to remove macroscopic disease, and preservation of lung parenchyma via extended pleurectomy/decortication may be preferable to extrapleural pneumonectomy.
恶性胸膜间皮瘤是一种侵袭性强、致命性的癌症，通常需要多个医学专业的参与。在过去几十年中，随着化疗、放疗和免疫治疗方面证据的增加和不断的进展，治疗方法也在不断发展；然而，尚未确定标准的治疗方案。无论总体策略如何，手术仍然是治疗的基础，以去除宏观疾病，并通过广泛的胸膜切除术/剥除术保留肺实质，可能优于胸膜外全肺切除术。
