Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, One Gustav L. Levy Place - Box 1236, New York, NY 10029, USA.
Thorac Surg Clin. 2020 Nov;30(4):473-480. doi: 10.1016/j.thorsurg.2020.08.006. Epub 2020 Sep 12.
The treatment of malignant pleural mesothelioma with radiation therapy has always been a technical challenge. For many years, radiation therapy was delivered after extrapleural pneumonectomy with acceptable results. As the utilization of pleurectomy/decortication increased, techniques, such as pleural intensity-modulated radiation therapy (IMRT) have been introduced. The experience with these techniques have grown and multiple trials using IMRT, both in the setting of extrapleural pneumonectomy or pleurectomy, are being conducted to assess its effectiveness.
胸膜恶性间皮瘤的放射治疗一直是一个技术挑战。多年来，在接受胸膜外全肺切除术（extrapleural pneumonectomy）后进行放射治疗，取得了可接受的结果。随着胸膜切除术/剥脱术（pleurectomy/decortication）的应用增加，出现了一些技术，如胸膜强度调制放射治疗（pleural intensity-modulated radiation therapy，IMRT）。这些技术的经验不断增加，多项使用 IMRT 的试验，无论是在胸膜外全肺切除术还是胸膜切除术的情况下，都在进行中，以评估其有效性。
