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新型冠状病毒肺炎患者的缺血性-出血性卒中

Ischemic-hemorrhagic stroke in patients with Covid-19.

作者信息

Azpiazu Landa N, Velasco Oficialdegui C, Intxaurraga Fernández K, Gonzalez Larrabe I, Riaño Onaindia S, Telletxea Benguria S

机构信息

Servicio de Anestesia y Reanimación, Hospital de Galdakao, Galdakao, Bizkaia, España.

Servicio de Anestesia y Reanimación, Hospital de Galdakao, Galdakao, Bizkaia, España.

出版信息

Rev Esp Anestesiol Reanim (Engl Ed). 2020 Nov;67(9):516-520. doi: 10.1016/j.redar.2020.08.002. Epub 2020 Oct 2.

Abstract

Coronavirus associated severe acute respiratory syndrome (SARS-CoV-2) causes a worldwide syndrome called Covid-19 that has caused 5,940,441 infections and 362,813 deaths until May 2020. In moderate and severe stages of the infection a generalized swelling, cytokine storm and an increment of the heart damage biomarkers occur. In addition, a relation between Covid-19 and neurological symptoms have been suggested. The results of autopsies suggest thrombotic microangiopathy in multiple organs. We present 2 cases of patients infected with severe Covid-19 that were hospitalized in the Reanimation Unit that presented cerebrovascular symptoms and died afterwards. A high dose prophylaxis with antithrombotic medication is recommended in patients affected by moderate to severe Covid-19.

摘要

冠状病毒相关的严重急性呼吸综合征(SARS-CoV-2)引发了一种名为新冠肺炎的全球综合征,截至2020年5月,该综合征已导致5940441例感染和362813例死亡。在感染的中重度阶段,会出现全身性肿胀、细胞因子风暴以及心脏损伤生物标志物增加的情况。此外,已有研究表明新冠肺炎与神经症状之间存在关联。尸检结果显示多个器官出现血栓性微血管病。我们报告2例感染严重新冠肺炎的患者,他们在复苏病房住院,出现了脑血管症状,随后死亡。建议对中重度新冠肺炎患者进行高剂量抗血栓药物预防治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44cd/7529602/91b750d6f1da/gr1_lrg.jpg

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