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经皮治疗良性胆肠吻合口狭窄:带固定缝线的可回收覆膜自膨式金属支架与大口径导管的比较。

Percutaneous Treatment of Benign Biliary Anastomotic Strictures: Retrievable Covered Self-Expandable Metal Stent with Fixation String Versus Large-Bore Catheters.

机构信息

Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North of Guangzhou Avenue, Guangzhou, China.

Division of Vascular and Interventional Radiology, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North of Guangzhou Avenue, Guangzhou, China.

出版信息

J Vasc Interv Radiol. 2021 Jan;32(1):113-120. doi: 10.1016/j.jvir.2020.01.034. Epub 2020 Oct 2.

Abstract

PURPOSE

To retrospectively compare the safety and efficacy of a covered self-expandable metal stent (CSEMS) with a transhepatic fixation string and a large-bore catheter for benign biliary anastomotic stricture after hepatobiliary surgery.

MATERIALS AND METHODS

From March 2012 to June 2017, 49 patients with benign biliary anastomotic strictures, untreatable with endoscopy, were included. Twenty-three patients (catheter group) were treated with a large-bore catheter (with progressive catheter upsizing to 16-18 Fr), whereas 26 patients (stent group) were treated by CSEMS (10-mm stent) placement. Technical success, clinical success, primary patency, recurrent strictures, complication rate, and catheter or stent indwelling time were compared between the groups.

RESULTS

Technical success and clinical success were achieved in all patients. In the stent group, stent retrieval was successful in all patients. The overall complication rate was 24.5% (catheter group vs. stent group, 30.4% vs. 19.2%; P = .363). Stent migration occurred in 1 patient during follow-up (1/26, 3.8%). The mean indwelling time was 10.3 ± 3.0 months (range, 8-16 months; median, 10 months) in the catheter group and 4.0 ± 1.2 months (range, 3-7 months; median, 4 months) in the stent group (P < .001). Recurrent strictures occurred in 10 (43.5%) patients in the catheter group and 4 (15.4%) patients in the stent group (P = .030). The 1- and 3-year primary patency rates were 82.6% and 69.3% in the catheter group and 92.3% and 84.4% in the stent group (P = .042).

CONCLUSIONS

Percutaneous placement of a retrievable CSEMS showed superior intermediate-term outcomes over a large-bore catheter in patients with benign biliary anastomotic strictures.

摘要

目的

回顾性比较经皮肝穿刺胆道引流固定导丝联合大口径引流管与覆膜自膨式金属支架(CSEMS)治疗肝胆手术后良性胆肠吻合口狭窄的安全性和有效性。

材料与方法

2012 年 3 月至 2017 年 6 月,纳入 49 例内镜治疗无效的良性胆肠吻合口狭窄患者。23 例患者(引流管组)采用大口径引流管(逐步更换为 16-18Fr 引流管)治疗,26 例患者(支架组)采用 CSEMS(10mm 支架)治疗。比较两组患者的技术成功率、临床成功率、一期通畅率、再狭窄率、并发症发生率、引流管或支架留置时间。

结果

所有患者均获得技术和临床成功。支架组所有患者均成功取出支架。总的并发症发生率为 24.5%(引流管组 vs. 支架组,30.4% vs. 19.2%;P =.363)。1 例患者在随访过程中发生支架迁移(1/26,3.8%)。引流管组的平均留置时间为 10.3 ± 3.0 个月(范围 8-16 个月;中位数 10 个月),支架组为 4.0 ± 1.2 个月(范围 3-7 个月;中位数 4 个月)(P <.001)。引流管组 10 例(43.5%)和支架组 4 例(15.4%)患者发生再狭窄(P =.030)。引流管组的 1 年和 3 年一期通畅率分别为 82.6%和 69.3%,支架组分别为 92.3%和 84.4%(P =.042)。

结论

对于良性胆肠吻合口狭窄患者,经皮穿刺放置可回收 CSEMS 优于大口径引流管,具有更好的中期效果。

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