病例报告：1例表现为眶尖综合征患者抗髓鞘少突胶质细胞糖蛋白（MOG）阳性
Case Report: Anti-myelin Oligodendrocyte Glycoprotein (MOG) Positive in a Patient Presented with Orbital Apex Syndrome.
作者信息
Kurathong Sireedhorn, Sanpatchayapong Anoma, Apiwattanakul Metha
机构信息
Department of Ophthalmology, Faculty of Medicine, Navamindradhiraj University, Bangkok, Thailand.
Department of Radiology, Faculty of Medicine, Navamindradhiraj University, Bangkok, Thailand.
出版信息
Neuroophthalmology. 2019 Feb 1;44(4):255-257. doi: 10.1080/01658107.2019.1571089.
A 60-year-old man presented with no light perception, ptosis and ophthalmoplegia in the right eye. The right fundus examination showed marked optic disc swelling. Serological tests for infectious and infiltrative diseases were all negative. Serum aquaporin-4 antibodies were negative, but anti-myelin oligodendrocyte glycoprotein (MOG) antibodies were positive. Magnetic resonance imaging revealed an extensive lesion in the right optic nerve with abnormal enhancement in the right orbital apex. His vision and eye movements improved after corticosteroid therapy. This report attests to the wide clinical phenotype possible in anti-MOG disease, including orbital apex syndrome.
一名60岁男性，右眼无光感、上睑下垂及眼球运动障碍。右眼眼底检查显示视盘明显肿胀。感染性和浸润性疾病的血清学检查均为阴性。血清水通道蛋白4抗体阴性，但抗髓鞘少突胶质细胞糖蛋白（MOG）抗体阳性。磁共振成像显示右侧视神经广泛病变，右侧眶尖异常强化。皮质类固醇治疗后，其视力和眼球运动有所改善。本报告证实了抗MOG疾病可能出现的广泛临床表型，包括眶尖综合征。
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