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对于接受唇腭裂手术的婴儿,术中补充葡萄糖是必不可少的吗?

Is intraoperative supplementation of dextrose essential for infants undergoing facial cleft surgeries?

作者信息

Rajan Sunil, Barua Kaushik, Tosh Pulak, Kumar Lakshmi

机构信息

Department of Anaesthesiology and Critical Care, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2020 Apr-Jun;36(2):162-165. doi: 10.4103/joacp.JOACP_318_18. Epub 2020 Jun 15.

Abstract

BACKGROUND AND AIMS

Dextrose is commonly added to the intraoperative maintenance fluids of pediatric patients. The primary objective was to evaluate the effect of addition of 1% dextrose to Ringer's lactate (RL) on blood glucose levels in infants undergoing facial cleft surgeries.

MATERIAL AND METHODS

This prospective, randomized, single blinded study was conducted in forty infants undergoing either cheiloplasty or palatoplasty. Random blood sugar (RBS) was assessed using a glucometer after induction of anaesthesia, and at 1 and 2 hours later. Group R received RL and Group D received RL with 1% dextrose as intraoperative maintenance fluid. Hypoglycemia was defined as RBS <70 mg/dL and hyperglycemia as RBS >150 mg/dL.

RESULTS

Baseline RBS levels and those at 60 min and 120 min post-induction were comparable in both groups. The increase in blood sugar levels from baseline to 60 min and to 120 min in each group was significant. Incidence of hyperglycemia was comparable in both groups. There were no episodes of hypoglycemia, intraoperatively.

CONCLUSION

Use of Ringer lactate alone or with addition of 1% dextrose resulted in comparable intraoperative blood sugar levels when used as maintenance fluid in infants undergoing facial cleft surgeries.

摘要

背景与目的

葡萄糖通常会添加到儿科患者的术中维持液中。主要目的是评估在乳酸林格氏液(RL)中添加1%葡萄糖对接受唇裂手术婴儿血糖水平的影响。

材料与方法

本前瞻性、随机、单盲研究在40例接受唇成形术或腭裂修复术的婴儿中进行。麻醉诱导后、1小时和2小时后使用血糖仪评估随机血糖(RBS)。R组接受乳酸林格氏液,D组接受含1%葡萄糖的乳酸林格氏液作为术中维持液。低血糖定义为RBS<70mg/dL,高血糖定义为RBS>150mg/dL。

结果

两组的基线RBS水平以及诱导后60分钟和120分钟时的水平相当。每组从基线到60分钟和120分钟血糖水平的升高均具有显著性。两组高血糖的发生率相当。术中无低血糖发作。

结论

在接受唇裂手术的婴儿中,单独使用乳酸林格氏液或添加1%葡萄糖作为维持液时,术中血糖水平相当。

相似文献

本文引用的文献

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Hypoglycemia in the neonate.新生儿低血糖症
Semin Perinatol. 2000 Apr;24(2):136-49. doi: 10.1053/sp.2000.6364.
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Surgical stress and neuroendocrine responses in infants and children.婴幼儿手术应激与神经内分泌反应
J Pediatr Endocrinol Metab. 1995 Jul-Sep;8(3):187-94. doi: 10.1515/jpem.1995.8.3.187.

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