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Contemporary outcomes in the detection of prostate cancer using transrectal ultrasound-guided 12-core biopsy in Singaporean men with elevated prostate specific antigen and/or abnormal digital rectal examination.在新加坡前列腺特异性抗原升高和/或直肠指检异常的男性中,使用经直肠超声引导下12针活检检测前列腺癌的当代结果。
Asian J Urol. 2015 Oct;2(4):187-193. doi: 10.1016/j.ajur.2015.08.003. Epub 2015 Sep 3.
3
Detection rate of prostate cancer following biopsy among the northern Han Chinese population: a single-center retrospective study of 1022 cases.在中国北方汉族人群中,前列腺癌活检后的检出率:一项 1022 例的单中心回顾性研究。
World J Surg Oncol. 2017 Aug 29;15(1):165. doi: 10.1186/s12957-017-1238-9.
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TRUS Biopsy Yield in Indian Population: A Retrospective Analysis.印度人群经直肠超声引导下活检的取材率:一项回顾性分析。
J Clin Diagn Res. 2017 Feb;11(2):PC01-PC05. doi: 10.7860/JCDR/2017/25473.9251. Epub 2017 Feb 1.
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Epidemiology of prostate cancer in India.印度前列腺癌的流行病学
Meta Gene. 2014 Aug 29;2:596-605. doi: 10.1016/j.mgene.2014.07.007. eCollection 2014 Dec.
6
Prostate biopsy findings in Indian men: a hospital-based study.印度男性前列腺活检结果:一项基于医院的研究。
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7
Detection rate of prostate cancer using prostate specific antigen in patients presenting with lower urinary tract symptoms: a retrospective study.在出现下尿路症状的患者中使用前列腺特异性抗原检测前列腺癌:一项回顾性研究。
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Optimal site and number of biopsy cores according to prostate volume prostate cancer detection in Korea.韩国根据前列腺体积确定前列腺癌检测的最佳活检部位和活检针数。
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9
Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: a systematic review.系统活检方法在前列腺癌诊断中的价值:一项系统评价
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Extended 12-core prostate biopsy increases both the detection of prostate cancer and the accuracy of Gleason score.扩展的12针前列腺穿刺活检可提高前列腺癌的检出率及Gleason评分的准确性。
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前列腺特异性抗原(PSA)大于50 ng/dL的患者经直肠超声引导下有限穿刺活检的结果:我们能否在不影响结果的情况下减少穿刺针数?

Outcome of TRUS Biopsy with Limited Cores in Patients with PSA More Than 50 ng/dL: Can We Reduce the Number of Cores Without Affecting Outcomes?

作者信息

Laddha Abhishek, Thomas Appu, Nair Deepak Chandran, Ravindran Greeshma C, Pooleri Ginil Kumar

机构信息

Department of Urology, Amrita Institute of Medical Sciences and Research Center, AIMS Ponekkara, P.0, Kochi, Kerala 682041 India.

Department of Biostatistics, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala India.

出版信息

Indian J Surg Oncol. 2020 Sep;11(3):509-512. doi: 10.1007/s13193-020-01165-9. Epub 2020 Jul 13.

DOI:10.1007/s13193-020-01165-9
PMID:33013136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7501352/
Abstract

The aims of our study were to see outcomes of limited core biopsy and compare its outcomes with standard 12-core biopsy in patients with PSA more than 50 ng/dL. We did a retrospective analysis of 149 patients undergoing prostatic biopsy with PSA more than 50 ng/dL between January 2014 and December 2018. Out of 149 patients, 49 underwent limited core (2 to 6 cores) TRUS biopsy with no systemic 12-core biopsy. Other 100 patients underwent standard 12-core biopsy under TRUS guidance. Total of 149 patient's records were analyzed and were included in the final analysis. There was no significant difference in demographics and prostate-specific antigen among the cohorts. All 49 patients in limited core TRUS biopsy had a positive biopsy with no need of re-biopsy. Fourteen out of 100 patients in TRUS biopsy had a negative biopsy. All 14 patients with negative biopsy had an average follow-up of 3.8 years with no conversion to positive biopsy. Patients with PSA more than 50 ng/dL and high clinical suspicion of prostate cancer can undergo limited core biopsy without systemic 12-core biopsy. In patients with no clinical evidence of prostate cancer, 12-core biopsy remains the gold standard for evaluation of prostate cancer.

摘要

我们研究的目的是观察局限性穿刺活检的结果,并将其结果与前列腺特异性抗原(PSA)大于50 ng/dL患者的标准12针穿刺活检结果进行比较。我们对2014年1月至2018年12月期间149例接受前列腺穿刺活检且PSA大于50 ng/dL的患者进行了回顾性分析。在这149例患者中,49例接受了局限性穿刺(2至6针)经直肠超声(TRUS)引导下穿刺活检,未进行系统性12针穿刺活检。另外100例患者在TRUS引导下接受了标准12针穿刺活检。对149例患者的记录进行了分析并纳入最终分析。各队列之间在人口统计学和前列腺特异性抗原方面无显著差异。局限性TRUS穿刺活检的49例患者穿刺结果均为阳性,无需再次穿刺。TRUS穿刺活检的100例患者中有14例穿刺结果为阴性。所有14例穿刺结果为阴性的患者平均随访3.8年,均未转变为穿刺阳性结果。PSA大于50 ng/dL且高度怀疑前列腺癌的患者可进行局限性穿刺活检,无需系统性12针穿刺活检。对于无前列腺癌临床证据的患者,12针穿刺活检仍是评估前列腺癌的金标准。