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粘质沙雷氏菌O9假定O特异性多糖的结构研究。

Structural studies of the putative O-specific polysaccharide of Serratia marcescens O9.

作者信息

Oxley D, Wilkinson S G

出版信息

Eur J Biochem. 1987 Jul 15;166(2):421-4. doi: 10.1111/j.1432-1033.1987.tb13532.x.

Abstract

A polymeric fraction containing the putative O-antigen has been isolated from the lipopolysaccharide of the reference strain (CDC 4534-60) for serogroup O9 of Serratia marcescens. The major component of the fraction was a polymer with a disaccharide repeating-unit of L-rhamnose (Rha) and 2-acetamido-2-deoxy-D-galactose (GalNAc) with the following structure:----3)D-GalpNAc(beta 1----3)L-Rhap(alpha 1----. Evidence for the presence in the fraction of a similar, minor polymer containing 4-substituted rhamnose residues was provided by the NMR spectra, methylation analysis, and Smith degradation.

摘要

已从粘质沙雷氏菌O9血清群参考菌株(CDC 4534-60)的脂多糖中分离出一种含有假定O抗原的聚合级分。该级分的主要成分是一种聚合物,其具有L-鼠李糖(Rha)和2-乙酰氨基-2-脱氧-D-半乳糖(GalNAc)的二糖重复单元,结构如下:----3)D-GalpNAc(β1----3)L-Rhap(α1----。核磁共振光谱、甲基化分析和史密斯降解为该级分中存在类似的、含有4-取代鼠李糖残基的次要聚合物提供了证据。

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