Oxley D, Wilkinson S G
Department of Chemistry, The University, Hull, Great Britain.
Carbohydr Res. 1988 Apr 1;175(1):111-7. doi: 10.1016/0008-6215(88)80161-7.
Partially acetylated glucorhamnans have been isolated from the lipopolysaccharides of three strains of Serratia marcescens. The polymer from the reference strain (C.D.C. 864-57) for serogroup O4 has the disaccharide repeating-unit shown below, in which acetylation at position 2 of the rhamnosyl residue is approximately 90% complete. Similar glucorhamnans from the reference strain (C.D.C. 843-57) for serogroup O7 and from a pigmented strain (NM) of serogroup O14 differ only in the configuration of the L-rhamnopyranosyl residue (beta) and the extent of O-acetylation (O7, almost stoichiometric; NM, 80-90%). Glucorhamnans of the second type have been isolated previously from the lipopolysaccharides of other strains of S. marcescens, including the reference strain for serogroup O6 and another pigmented O14 strain (N.C.T.C. 1377). In all cases, the lipopolysaccharide extracts also contained acidic glycans, but the glucorhamnans are believed to constitute the integral side-chains. (Formula: see text).
已从三株粘质沙雷氏菌的脂多糖中分离出部分乙酰化的葡糖鼠李聚糖。血清群O4参考菌株（美国疾病控制与预防中心864 - 57）的聚合物具有如下所示的二糖重复单元，其中鼠李糖基残基2位的乙酰化约90%完成。血清群O7参考菌株（美国疾病控制与预防中心843 - 57）和血清群O14的一株色素产生菌株（NM）的类似葡糖鼠李聚糖仅在L - 鼠李吡喃糖基残基的构型（β）和O - 乙酰化程度上有所不同（O7，几乎化学计量；NM，80 - 90%）。第二类葡糖鼠李聚糖先前已从其他粘质沙雷氏菌菌株的脂多糖中分离出来，包括血清群O6的参考菌株和另一株色素产生的O14菌株（英国国家典型培养物保藏中心1377）。在所有情况下，脂多糖提取物中也含有酸性聚糖，但葡糖鼠李聚糖被认为构成完整的侧链。（分子式：见正文）
