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曲霉酶的抗炎特性——一种具有蛋白水解作用的新型酶类物质

[Anti-inflammatory properties of asperase--a new enzymatic substance with proteolytic action].

作者信息

Maslov N F, Liubetskaia Zh A

出版信息

Farmakol Toksikol. 1987 May-Jun;50(3):100-2.

PMID:3301396
Abstract

The anti-inflammatory effect of asperase was shown on models of protein, aerosil and formalin edemas. The effect was the same as that of trypsin and was more pronounced as compared with that of chymotrypsin. Intramuscular administration of asperase stimulated the growth of granulation tissue as well. Inhibition of the enzyme activity with respect to a high molecular protein (casein) had no influence on the manifestation of its anti-inflammatory effect.

摘要

曲霉酶在蛋白质、气凝胶和福尔马林水肿模型上显示出抗炎作用。其作用与胰蛋白酶相同,与糜蛋白酶相比更为显著。肌内注射曲霉酶也刺激肉芽组织生长。对高分子蛋白质(酪蛋白)的酶活性抑制对其抗炎作用的表现没有影响。

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