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多黏菌素B引起的皮肤色素沉着过度。

Polymyxin B-Induced Skin Hyperpigmentation.

作者信息

Wen Xueke, Luo Chunliu, Lyu Weitao

机构信息

The First Clinical Medical College of Jinan University, No. 601 Huangpu Avenue West, Guangzhou City 510630, Guangdong Province, China.

The First Affiliated Hospital of Jinan University, No. 613 Huangpu Avenue West, Guangzhou City 510630, Guangdong Province, China.

出版信息

Case Rep Med. 2020 Sep 18;2020:6461329. doi: 10.1155/2020/6461329. eCollection 2020.

Abstract

Polymyxin B-induced skin hyperpigmentation is a rare adverse drug reaction (ADR). In this report, we present the case of a patient who underwent an abscess resection with right epididymitis, in which a multidrug-resistant infection (KPI) is formed. The patient was treated with polymyxin B and subsequently developed skin hyperpigmentation and desquamation. The desquamation improved and the pigmentation gradually returned to normal after sixty days after the withdrawal of polymyxin B.

摘要

多粘菌素B引起的皮肤色素沉着是一种罕见的药物不良反应(ADR)。在本报告中,我们介绍了一例患者,该患者因右附睾炎接受脓肿切除术,术中形成了多重耐药感染(KPI)。患者接受了多粘菌素B治疗,随后出现皮肤色素沉着和脱屑。停药60天后,脱屑情况改善,色素沉着逐渐恢复正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/7519980/7e19f818b513/CRIM2020-6461329.001.jpg

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Polymyxin B-Induced Skin Hyperpigmentation.多黏菌素B引起的皮肤色素沉着过度。
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本文引用的文献

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Drug-Induced Hyperpigmentation: Review and Case Series.药物诱导性色素沉着:综述与病例系列。
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Colistin neurotoxicity: revisited.黏菌素神经毒性:再探讨
BMJ Case Rep. 2015 Jul 23;2015:bcr2015210787. doi: 10.1136/bcr-2015-210787.
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