Krempf M, Marre M
Diabete Metab. 1987 Jun;13(3):225-31.
The term "microalbuminuria" qualifies an albumin excretion rate above the upper limit of normal individuals but below values giving positive results with conventional test strips. Its predictive value has been established for diabetic nephropathy in type I Diabetes, and for an excessive risk for mortality in type II Diabetes. Microalbuminuria is of glomerular origin in diabetes. It is secondary both to intra-renal haemodynamic changes and to altered permeability of the glomerular basement membrane. The various parameters involved in its genesis are reviewed.
术语“微量白蛋白尿”指的是白蛋白排泄率高于正常个体的上限,但低于传统试纸检测呈阳性的数值。其预测价值已在1型糖尿病的糖尿病肾病以及2型糖尿病的过高死亡风险中得到证实。糖尿病中的微量白蛋白尿起源于肾小球。它继发于肾内血流动力学变化和肾小球基底膜通透性改变。本文综述了其发生过程中涉及的各种参数。