School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Biomed Res Int. 2020 Sep 15;2020:9321246. doi: 10.1155/2020/9321246. eCollection 2020.
This study aims at investigating differences in oral cancer (OC) incidence trends between two populations in Taiwan and Thailand.
We used the population-based cancer registry data from Taiwan (1979-2016) and Khon Kaen (KK), Thailand (1985-2016). We performed joinpoint analyses to detect the trend change points for the OC incidence and to quantify the time trends in both sexes and regions. Age-period-cohort curves were plotted to explain the incidence trends.
In Taiwan, the estimated annual increases in OC were approximately 6.0% in males, although the increase slowed after 2009, and 2.6% in females. In KK, the OC incidence steadily decreased by -2.5% per year in females, but there was no obvious change in males. A strong period effect observed in those aged 45-69 years in Taiwanese males resulted in a peak incidence in the middle age group. Decreased period and cohort effects were observed in females in KK.
Taiwanese males are the predominant sex affected by OC in Taiwan, and the trend has decelerated since 2009. Age, period, and cohort effects were different between males and females in the two regions.
本研究旨在调查台湾和泰国两个地区口腔癌（OC）发病率趋势的差异。
我们使用了来自台湾（1979-2016 年）和泰国孔敬府（1985-2016 年）的基于人群的癌症登记数据。我们进行了 Joinpoint 分析，以检测 OC 发病率的趋势变化点，并量化两性和地区的时间趋势。绘制年龄-时期-队列曲线以解释发病趋势。
在台湾，男性 OC 的估计年增长率约为 6.0%，尽管自 2009 年以来增速有所放缓，女性增长率为 2.6%。在孔敬府，女性 OC 的发病率每年稳定下降 2.5%，但男性没有明显变化。在台湾男性中，45-69 岁年龄组的强烈时期效应导致中年组的发病率达到高峰。在孔敬府的女性中，观察到时期和队列效应下降。
台湾男性是台湾 OC 的主要发病群体，自 2009 年以来，发病趋势已放缓。两个地区的男性和女性在年龄、时期和队列效应方面存在差异。
