Shields Lisa B E, White Jeffrey T, Peppas Dennis S, Rosenberg Eran
Norton Neuroscience Institute, Norton Healthcare, Louisville, KY, USA.
Norton Children's Urology, Norton Healthcare, Louisville, KY, USA.
Glob Pediatr Health. 2020 Sep 23;7:2333794X20958929. doi: 10.1177/2333794X20958929. eCollection 2020.
Cloaca is a common excretory channel for the genital, urinary, and gastrointestinal tracts. It is considered a severe anorectal malformation caused by failed partitioning of the genital, rectal, and urinary tracts.
We report 5 infants with cloaca at birth who were identified prenatally by one or more of the following on prenatal ultrasound (US): ambiguous genitalia, a cystic pelvic/abdominal mass, hydronephrosis, ascites, a single umbilical artery, and oligohydramnios.
A cystic pelvic/abdominal mass and ambiguous genitalia were each observed in 3 cases by prenatal US. Ambiguous genitalia was observed in all 5 neonates at birth. There were 2 twin pregnancies (dichorionic/diamniotic and monochorionic/monoamniotic), with only 1 twin in a set affected with cloaca.
Pediatricians should be alert to the prenatal US findings that may raise suspicion of a persistent cloaca to improve both prenatal counseling and family preparation.
泄殖腔是生殖、泌尿和胃肠道的共同排泄通道。它被认为是一种严重的肛门直肠畸形，由生殖、直肠和泌尿道的分隔失败引起。
我们报告了5例出生时患有泄殖腔的婴儿，他们在产前超声（US）检查中通过以下一种或多种情况在产前被识别出来：生殖器模糊、盆腔/腹部囊性肿块、肾积水、腹水、单脐动脉和羊水过少。
产前超声检查在3例中均观察到盆腔/腹部囊性肿块和生殖器模糊。出生时所有5例新生儿均观察到生殖器模糊。有2例双胎妊娠（双绒毛膜/双羊膜囊和单绒毛膜/单羊膜囊），每组中只有1例双胎受泄殖腔影响。
儿科医生应警惕可能提示持续性泄殖腔的产前超声检查结果，以改善产前咨询和家庭准备。
