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无氟与传统输尿管镜治疗尿路结石的比较:系统评价和荟萃分析。

Fluoroless versus conventional ureteroscopy for urinary stones: a systematic review and meta-analysis.

机构信息

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China -

出版信息

Minerva Urol Nephrol. 2021 Jun;73(3):299-308. doi: 10.23736/S2724-6051.20.04042-4. Epub 2020 Oct 5.

Abstract

INTRODUCTION

The aim of this review was to comprehensively assess the effectiveness and safety of fluoroless ureteroscopy (URS) vs. conventional URS for urinary stones.

EVIDENCE ACQUISITION

An exhaustive search on PubMed, EMBASE, Web of Science and Cochrane Library were performed to find eligible research before May 2020. Result parameters including stone-free rate (SFR), operation time, repeat procedure rate and complication rate were assessed using RevMan 5.3 (Cochrane Training; https://training.cochrane.org/online-learning/core-software-cochrane-reviews/revman/revman-5-download).

EVIDENCE SYNTHESIS

Seven studies (5 retrospective studies and 2 prospective randomized controlled trials) involving 1404 individuals were included. Pooled results demonstrated that the operation time in fluoroless URS group was slightly longer than conventional URS group (weighted mean difference [MD]=2.79, P=0.0001), but no statistically significant differences regarding SFR (odds ratio [OR]=1.18, P=0.57), repeat procedure rate (OR=1.32, P=0.52), and total complication rate (OR=0.75, P=0.16) were observed between two techniques.

CONCLUSIONS

Flourless URS is equally safe and effective to conventional URS procedure with zero radiation exposure. However, it needs to be cautiously conducted in selected patients and fluoroscopy equipment should always be available intraoperatively.

摘要

简介

本综述旨在全面评估无氟输尿管镜检查(URS)与传统 URS 治疗尿路结石的有效性和安全性。

证据采集

本研究于 2020 年 5 月前在 PubMed、EMBASE、Web of Science 和 Cochrane Library 上进行了全面检索,以查找合格的研究。使用 RevMan 5.3(Cochrane 培训;https://training.cochrane.org/online-learning/core-software-cochrane-reviews/revman/revman-5-download)评估结石清除率(SFR)、手术时间、重复程序率和并发症发生率等结果参数。

证据综合

共纳入 7 项研究(5 项回顾性研究和 2 项前瞻性随机对照试验),涉及 1404 例患者。汇总结果表明,无氟 URS 组的手术时间略长于传统 URS 组(加权均数差 [MD]=2.79,P=0.0001),但在 SFR(比值比 [OR]=1.18,P=0.57)、重复程序率(OR=1.32,P=0.52)和总并发症发生率(OR=0.75,P=0.16)方面无统计学差异。

结论

无氟 URS 与传统 URS 具有相同的安全性和有效性,且无辐射暴露。然而,它需要在选定的患者中谨慎进行,并且术中应始终备有透视设备。

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