241876Joint Pathology Center, Silver Spring, MD, USA.
Northwest ZooPath, Monroe, WA, USA.
Vet Pathol. 2020 Nov;57(6):880-884. doi: 10.1177/0300985820943539. Epub 2020 Oct 5.
Odontogenic lesions are well described in domestic cats, but published literature describing these lesions in nondomestic felids is limited. This study reports oral lesions in 109 captive, non-domestic felids. Ten cases of odontogenic lesions were diagnosed, including 9 with fibromatous epulis of periodontal ligament origin (FEPLO) and one odontogenic cyst in a cougar. FEPLO was common in lions. FEPLO did not recur after surgical removal in any of the 3 cases for which follow-up information was available. Increased occurrences of oral papillomas in snow leopards and eosinophilic granulomas in tigers were identified, which is consistent with the reported literature. With the exception of oral papillomas in snow leopards and FEPLO in lions, the spectrum of oral lesions in nondomestic felids was similar to what is reported in domestic cats, with squamous cell carcinoma being the most common oral malignancy, and stomatitis/gingivitis/glossitis accounting for approximately one third of all cases. Rare diagnoses with one case each included hemangioma, fibrosarcoma, melanoma, cleft palate, and glossal amyloidosis.
牙源性病变在宠物猫中已有详尽描述，但关于非宠物猫的牙源性病变的文献报道却十分有限。本研究报告了 109 只圈养非宠物猫的口腔病变。诊断出 10 例牙源性病变，其中 9 例为牙周韧带纤维瘤性龈瘤（FEPLO），1 例美洲狮牙源性囊肿。FEPLO 在狮子中较为常见。在可获得随访信息的 3 例中，手术后均无复发。雪豹口腔乳头状瘤和老虎嗜酸性肉芽肿的发生率增加，这与文献报道一致。除了雪豹的口腔乳头状瘤和狮子的 FEPLO 之外，非宠物猫的口腔病变谱与家猫相似，鳞状细胞癌是最常见的口腔恶性肿瘤，约三分之一的病例为口炎/牙龈炎/舌炎。其他罕见诊断包括血管瘤、纤维肉瘤、黑色素瘤、腭裂和舌淀粉样变性各 1 例。
