Schreiner Philipp, Biedermann Luc, Greuter Thomas, Wright Benjamin L, Straumann Alex
Department of Gastroenterology & Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, AZ, USA.
Dis Esophagus. 2021 Jan 11;34(1). doi: 10.1093/dote/doaa105.
As the awareness among gastroenterologists regarding endoscopic features suggesting eosinophilic esophagitis is increasing, individuals without symptoms of esophageal dysfunction are increasingly being found to have esophageal eosinophilia on biopsies performed during upper gastrointestinal endoscopies. However, the course of disease and the management of these asymptomatic individuals with esophageal eosinophilia remain elusive. In this review, we propose a definition of asymptomatic individuals with esophageal eosinophilia and discuss the prevalence, risk factors, and course of disease of this specific patient group. Furthermore, we have established a diagnostic and therapeutic pathway based on the most recent available data.
随着胃肠病学家对提示嗜酸性食管炎的内镜特征的认识不断提高，在上消化道内镜检查时进行活检发现，越来越多没有食管功能障碍症状的个体存在食管嗜酸性粒细胞增多。然而，这些无症状食管嗜酸性粒细胞增多个体的疾病进程和管理方法仍不明确。在本综述中，我们提出了无症状食管嗜酸性粒细胞增多个体的定义，并讨论了这一特定患者群体的患病率、危险因素和疾病进程。此外，我们根据最新可得数据建立了诊断和治疗路径。
