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营养师主导的极低卡路里饮食(VLCD)模式对肥胖患者进行术前非减重手术的减肥效果。

Efficacy of a dietitian-led very low calorie diet (VLCD) based model of care to facilitate weight loss for obese patients prior to elective, non-bariatric surgery.

机构信息

Department of Nutrition & Dietetics, Logan Hospital, Loganholme, QLD, Australia.

School of Allied Health Sciences, Griffith University, Gold Coast, QLD, Australia.

出版信息

J Hum Nutr Diet. 2021 Feb;34(1):188-198. doi: 10.1111/jhn.12819. Epub 2020 Oct 5.

DOI:10.1111/jhn.12819
PMID:33016501
Abstract

BACKGROUND

Elective surgery in obese adults carries a higher risk of post-operative infection and prolonged hospital stays, and surgeons may postpone surgery for patients with obesity until they lose weight. The present study aimed to determine the efficacy of a dietitian-led very low calorie diet (VLCD)-based model of care with respect to achieving weight loss for obese patients prior to surgery.

METHODS

This mixed-methods study included a medical chart audit of patients referred to a VLCD-based model over 23 months, as well as a survey of recently treated patients and surgeons who utilised the model. Preoperative weight loss targets were set by surgeons, and the dietitian prescribed individualised VLCD-based treatment. Efficacy was determined as weight loss considered sufficient for surgery, clinical safety of VLCD-based treatment, feasibility, and stakeholder value. Pre/post-intervention differences in clinical measures were explored by paired t-test or Wilcoxon tests as appropriate.

RESULTS

Data on seventy-eight eligible patients [mean (SD) 45 (13) years, 90% female, body mass index 44.3 (6.2) kg m ] demonstrated significant mean (SD) weight loss of 7.4% (5.3%) body weight (P < 0.05). Most patients (70%, n = 50/71) achieved sufficient weight loss to proceed to surgery. Fifty-six per cent of patients reported mild side effects (n = 43/77) and none led to treatment cessation. Surgeons reported VLCD-based treatment made operations easier (83%, n = 10/12) and shorter (75%, n = 9/12) and all recommended the model of care. All surveyed patients (n = 24) reported satisfaction with their VLCD-based model experience.

CONCLUSIONS

A dietitian-led VLCD-based model achieved sufficient weight loss to facilitate elective surgery for most patients. The approach was feasible, highly valued by patients and surgeons, and resulted in perceived surgical benefits.

摘要

背景

肥胖成年人的择期手术术后感染风险较高,住院时间延长,外科医生可能会推迟肥胖患者的手术,直到他们减肥。本研究旨在确定营养师主导的极低卡路里饮食(VLCD)为肥胖患者提供术前减肥的效果。

方法

这项混合方法研究包括对 23 个月来接受 VLCD 模型治疗的患者进行病历审核,以及对最近接受治疗的患者和使用该模型的外科医生进行调查。术前体重减轻目标由外科医生设定,营养师开个性化 VLCD 治疗方案。疗效通过外科医生认为手术减肥效果足够、VLCD 治疗的临床安全性、可行性和利益相关者价值来确定。通过配对 t 检验或 Wilcoxon 检验等适当方法探索临床测量的干预前后差异。

结果

纳入 78 名符合条件的患者(平均[标准差]45[13]岁,90%为女性,体重指数 44.3[6.2]kg/m )数据显示体重显著减轻 7.4%(5.3%)(P<0.05)。大多数患者(70%,n=50/71)体重减轻足够进行手术。56%的患者报告有轻度副作用(n=43/77),无一人因副作用停止治疗。外科医生报告说 VLCD 治疗使手术更容易(83%,n=10/12)和更短(75%,n=9/12),并全部推荐这种治疗模式。所有接受调查的患者(n=24)均报告对其 VLCD 治疗模式感到满意。

结论

营养师主导的 VLCD 模型为大多数患者提供了足够的体重减轻,以促进择期手术。该方法可行,深受患者和外科医生的重视,并带来了手术效益。

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