Department of Chemical Sciences, University of Napoles Federico II, Complesso Universitario Monte S. Angelo, Napoli, Italy.
Faculty of Agriculture, Department of Plant Protection, University of Kurdistan, Sanandaj, Iran.
Nat Prod Res. 2021 Dec;35(24):5857-5861. doi: 10.1080/14786419.2020.1797731. Epub 2020 Oct 5.
Two phytotoxic furan derivatives were isolated, together with the well-known fungal and plant phytotoxin tyrosol, from the culture filtrates of . This fungal pathogen isolated from trees induced wood necrosis and decline symptoms on the host plant in Iran. The two furan derivatives, isolated for the first time from , were identified by spectroscopic methods (essentially 1 D and 2 D H and C NMR and ESIMS spectroscopy) as 5-hydroxymethylfuraldehyde and 2,5-dihydroxymethylfuran. The phytotoxic activity of the three metabolites was evaluated by leaf puncture assay on holm oak ( L.) and tomato ( L.) leaves. All compounds induced necrosis on holm oak leaves while very low toxicity was showed against tomato leaves. The two furan derivatives were more toxic than tyrosol and particularly 5-hydroxymethylfuraldehyde was the most phytotoxic compound.
从 分离的真菌病原体引起了伊朗宿主植物的木质部坏死和衰退症状。从该真菌病原体的培养滤液中分离到两种已知的真菌和植物植物毒素——酪醇和两种植物毒性呋喃衍生物。这两种呋喃衍生物为首次从 中分离得到，通过光谱方法（主要是 1D 和 2D H 和 C NMR 和 ESIMS 光谱）鉴定为 5-羟甲基糠醛和 2,5-二羟甲基呋喃。通过对油橄榄（L.）和番茄（L.）叶片进行叶穿刺试验评价了这三种代谢物的植物毒性。所有化合物均诱导油橄榄叶片坏死，而对番茄叶片表现出极低的毒性。两种呋喃衍生物比酪醇毒性更大，特别是 5-羟甲基糠醛是最具植物毒性的化合物。
