Brusca J, Summers M, Couch J, Courtney L
Intervirology. 1986;26(4):207-22. doi: 10.1159/000149703.
The host range of the insect virus Autographa californica nuclear polyhedrosis virus (AcMNPV) was examined. AcMNPV could not initiate a productive infection in frog, turtle, trout, or codling moth cell lines. After exposure to AcMNPV, neither viral DNA nor RNA synthesis could be detected in these cell lines as assayed by nucleic acid probe hybridization. Entry of AcMNPV nucleocapsids into the cytoplasm and viral DNA into the nucleus, however, was as efficient in the nonpermissive cell lines as it was in a permissive insect cell line. The data suggest that the block in AcMNPV infection in these nonpermissive cell lines is at a stage subsequent to viral DNA entry into the nucleus.
对昆虫病毒苜蓿银纹夜蛾核型多角体病毒（AcMNPV）的宿主范围进行了检测。AcMNPV无法在青蛙、乌龟、鳟鱼或苹果蠹蛾细胞系中引发有效感染。在暴露于AcMNPV后，通过核酸探针杂交检测发现，这些细胞系中均未检测到病毒DNA或RNA的合成。然而，AcMNPV核衣壳进入细胞质以及病毒DNA进入细胞核的过程，在非允许细胞系中的效率与在允许的昆虫细胞系中一样高。数据表明，在这些非允许细胞系中，AcMNPV感染的阻断发生在病毒DNA进入细胞核之后的阶段。
