Kyritsis Konstantinos, Fagerberg Petter, Ioakimidis Ioannis, Klingelhoefer Lisa, Reichmann Heinz, Delopoulos Anastasios
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:494-497. doi: 10.1109/EMBC44109.2020.9175615.
Parkinson's disease (PD) is the second most common age-related neurodegenerative disorder after Alzheimer's disease, associated, among others, with motor symptoms such as resting tremor, rigidity and bradykinesia. At the same time, early diagnosis of PD is hindered by a high misdiagnosis rate and the subjective nature of the diagnosis process itself. Recent developments in mobile and wearable devices, such as smartphones and smartwatches, have allowed the automated detection and objective measurement of PD symptoms. In this paper we investigate the hypothesis that PD motor symptom degradation can be assessed by studying the in-meal behavior and modeling the food intake process. To achieve this, we use the inertial data from a commercial smartwatch to investigate the in-meal eating behavior of healthy controls and PD patients. In addition, we define and provide a methodology for calculating Plate-to-Mouth (PtM), an indicator that relates with the average time that the hand spends transferring food from the plate towards the mouth during the course of a meal. The presented experimental results, using our collected dataset of 28 participants (7 healthy controls and 21 PD patients), support our hypothesis. Results initially point out that PD patients have a higher PtM value than the healthy controls. Finally, using PtM we achieve a precision/recall/F1 of 0.882/0.714/0.789 towards classifying the meals from the PD patients and healthy controls.
帕金森病(PD)是仅次于阿尔茨海默病的第二常见的与年龄相关的神经退行性疾病,与静止性震颤、僵硬和运动迟缓等运动症状有关。同时,PD的早期诊断受到高误诊率和诊断过程本身主观性的阻碍。移动和可穿戴设备(如智能手机和智能手表)的最新发展使得能够自动检测和客观测量PD症状。在本文中,我们研究了这样一个假设,即可以通过研究用餐行为和对食物摄入过程进行建模来评估PD运动症状的恶化。为了实现这一点,我们使用来自商业智能手表的惯性数据来研究健康对照者和PD患者的用餐行为。此外,我们定义并提供了一种计算“餐盘到嘴”(PtM)的方法,PtM是一个指标,与用餐过程中手将食物从餐盘转移到嘴的平均时间有关。使用我们收集的28名参与者(7名健康对照者和21名PD患者)的数据集得出的实验结果支持了我们的假设。结果最初指出,PD患者的PtM值高于健康对照者。最后,使用PtM,我们在区分PD患者和健康对照者的用餐方面实现了0.882/0.714/0.789的精确率/召回率/F1值。