Yamlome Pascal, Akwaboah Akwasi Darkwa, Marz Aylin, Deo Makarand
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:1144-1147. doi: 10.1109/EMBC44109.2020.9176594.
Breast cancer is a global health concern, with approximately 30 million new cases projected to be reported by 2030. While efforts are being channeled into curative measures, preventive and diagnostic measures also need to be improved to curb the situation. Convolutional Neural Networks (CNNs) are a class of deep learning algorithms that have been widely adopted for the computerized classification of breast cancer histopathology images. In this work, we propose a set of training techniques to improve the performance of CNN-based classifiers for breast cancer identification. We combined transfer learning techniques with data augmentation and whole image training to improve the performance of the CNN classifier. Instead of conventional image patch extraction for training and testing, we employed a high-resolution whole-image training and testing on a modified network that was pre-trained on the Imagenet dataset. Despite the computational complexity, our proposed classifier achieved significant improvement over the previously reported studies on the open-source BreakHis dataset, with an average image level accuracy of about 91% and patient scores as high as 95%.Clinical Relevance- this work improves on the performance of CNN for breast cancer histopathology image classification. An improved Breast cancer image classification can be used for the preliminary examination of tissue slides in breast cancer diagnosis.
乳腺癌是一个全球关注的健康问题,预计到2030年将报告约3000万新病例。在致力于采取治愈措施的同时,预防和诊断措施也需要改进以控制这种情况。卷积神经网络(CNN)是一类深度学习算法,已被广泛用于乳腺癌组织病理学图像的计算机化分类。在这项工作中,我们提出了一组训练技术来提高基于CNN的乳腺癌识别分类器的性能。我们将迁移学习技术与数据增强和全图像训练相结合,以提高CNN分类器的性能。我们没有采用传统的图像块提取进行训练和测试,而是在经过ImageNet数据集预训练的改进网络上进行高分辨率全图像训练和测试。尽管计算复杂度较高,但我们提出的分类器在开源BreakHis数据集上比先前报道的研究有了显著改进,平均图像级准确率约为91%,患者评分高达95%。临床相关性——这项工作提高了CNN在乳腺癌组织病理学图像分类方面的性能。改进的乳腺癌图像分类可用于乳腺癌诊断中组织切片的初步检查。