Ley Sebastian, Faenger Bernd, Hilger Ingrid, Helbig Marko
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:1795-1798. doi: 10.1109/EMBC44109.2020.9175940.
This contribution deals with the detection and imaging of magnetic modulated nanoparticles by means of ultra-wideband sensing. We performed phantom measurements in a practical measurement setup where the magnetic nanoparticles are modulated by a static and a low periodic changing external magnetic field. We investigated the influence of the modulation type of the polarizing magnetic field on both, detectability and imaging of magnetic nanoparticles. We can conclude that both modulations generate a sufficient contrast in order that the nanoparticles were detected at the correct position in a three-dimensional volume. The imaging results, including 32 channels, indicate that the two state (ON/OFF) modulation of the magnetic field under constant environmental conditions shows better results compared to a sinusoidal excitation of the magnetic field.
本文通过超宽带传感技术对磁调制纳米颗粒进行检测和成像。我们在实际测量装置中进行了体模测量，其中磁性纳米颗粒由静态和低周期性变化的外部磁场调制。我们研究了极化磁场的调制类型对磁性纳米颗粒的可检测性和成像的影响。我们可以得出结论，两种调制都产生了足够的对比度，以便在三维体积中的正确位置检测到纳米颗粒。包括32个通道的成像结果表明，在恒定环境条件下，磁场的双态（开/关）调制比磁场的正弦激励显示出更好的结果。
