Trambaiolli Lucas R, Cassani Raymundo, Falk Tiago H
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:3481-3484. doi: 10.1109/EMBC44109.2020.9175409.
Neurovascular coupling provides valuable descriptive information about neural function and communication. In this work, we propose to objectively characterize EEG sub-band modulation in an attempt to compare with local variations of fNIRS hemoglobin concentration. First, full-band EEG signals are decomposed into five well-known frequency sub-bands: delta, theta, alpha, beta, and gamma. The temporal amplitude envelope of each sub-band is then computed via Hilbert transformation. The proposed EEG 'spectro-temporal amplitude modulation' (EEG-AM) feature measures the rate at which each sub-band is modulated. Similarities between EEG-AM features and fNIRS hemoglobin concentration are computed for four neighboring channels over the occipital area during resting-state. Experiments with a database of 29 participants show statistically significant similarities between the total hemoglobin concentration and the alpha band modulating the alpha, beta, and gamma frequencies. These results support the idea that the EEG-AM can carry hemodynamic properties.Clinical relevance- This shows that the EEG spectro-temporal amplitude modulation present similarities with the hemoglobin concentration in co-placed channels.
神经血管耦合提供了有关神经功能和通信的有价值的描述性信息。在这项工作中，我们建议客观地表征脑电图子带调制，以便与功能近红外光谱血红蛋白浓度的局部变化进行比较。首先，全频段脑电图信号被分解为五个著名的频率子带：δ波、θ波、α波、β波和γ波。然后通过希尔伯特变换计算每个子带的时间幅度包络。所提出的脑电图“频谱-时间幅度调制”（EEG-AM）特征测量每个子带被调制的速率。在静息状态下，计算枕叶区域四个相邻通道的EEG-AM特征与功能近红外光谱血红蛋白浓度之间的相似性。对29名参与者的数据库进行的实验表明，总血红蛋白浓度与调制α波、β波和γ波频率的α波带之间存在统计学上的显著相似性。这些结果支持了EEG-AM可以携带血液动力学特性的观点。临床相关性——这表明脑电图频谱-时间幅度调制与共置通道中的血红蛋白浓度存在相似性。
