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用于评估肠道体内记录期间电极接触压力的压力传感器阵列设计

Design of Pressure Sensor Arrays to Assess Electrode Contact Pressure During In Vivo Recordings in the Gut.

作者信息

Athavale Omkar N, Paskaranandavadivel Niranchan, Angeli Timothy R, Avci Recep, Cheng Leo K

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:4204-4207. doi: 10.1109/EMBC44109.2020.9175843.

DOI:10.1109/EMBC44109.2020.9175843
PMID:33018924
Abstract

The gastrointestinal (GI) tract is in part controlled by slow wave electrical activity. Recordings of slow waves with high-resolution (HR) electrode arrays are used to characterize normal and abnormal conduction pathways. Improving the quality of these electrical recordings is important for developing a better understanding of abnormal activity. Contact pressure is one factor that can affect the quality of electrical recordings. We compared the performance of two pressure sensing devices for measuring HR electrode array contact pressure. A Velostat-based sensor array was custom designed and built in a 4 × 2 conguration (area: 30 mm per sensor) to be integrated into electrical recordings. Commercially available FlexiForce A201 sensors were used to compare to the Velostat-based sensors. Benchtop testing of these sensors was performed; the error of the Velostat-based sensors (14-31%) was better than that of the FlexiForce sensors (20-49%) within a range of 2666-6666 Pa. The Velostat-based sensors were also more repeatable than the FlexiForce sensors over the same pressure range. Simultaneous pressure and slow wave recordings were performed in vivo on a rabbit small intestine. The Velostat-based sensors were able to resolve spatiotemporal changes in contact pressure in the range of 0-10 000 Pa.

摘要

胃肠道部分受慢波电活动控制。使用高分辨率(HR)电极阵列记录慢波,以表征正常和异常传导通路。提高这些电记录的质量对于更好地理解异常活动很重要。接触压力是影响电记录质量的一个因素。我们比较了两种用于测量HR电极阵列接触压力的压力传感装置的性能。基于维乐斯塔(Velostat)的传感器阵列经过定制设计,采用4×2配置(每个传感器面积:30平方毫米),以便集成到电记录中。使用市售的FlexiForce A201传感器与基于维乐斯塔的传感器进行比较。对这些传感器进行了台式测试;在2666 - 6666帕的压力范围内,基于维乐斯塔的传感器的误差(14% - 31%)优于FlexiForce传感器(20% - 49%)。在相同压力范围内,基于维乐斯塔的传感器也比FlexiForce传感器更具重复性。在兔小肠上进行了体内压力和慢波同步记录。基于维乐斯塔的传感器能够分辨0 - 10000帕范围内接触压力的时空变化。

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