Gharib Isam, Sawan Mohamad
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5025-5028. doi: 10.1109/EMBC44109.2020.9176267.
We present in this work an array of microfluidic valves altogether with a corresponding custom control interface. This microfluidic network is an integrated drug delivery system intended for Organ-On-Chip (OOC) applications. Recent research works have achieved high-quality OOC platforms. The latter platforms require an increasing complexity and efficient and flexibile drug delivery systems. As many organs can be integrated in a single chip, a large number of micro-fluidic channels is needed to access various specific locations. Thus, we propose to drive the expected large number of switching valves with an embedded on-chip controller. The presented system includes a control interface of 5 channels using n-line control unit.
在这项工作中,我们展示了一系列微流控阀以及相应的定制控制接口。这个微流控网络是一个用于片上器官(OOC)应用的集成药物输送系统。最近的研究工作已经实现了高质量的OOC平台。后一种平台需要越来越复杂且高效灵活的药物输送系统。由于许多器官可以集成在单个芯片中,因此需要大量微流控通道来访问各个特定位置。因此,我们建议使用嵌入式片上控制器来驱动预期的大量开关阀。所展示的系统包括一个使用n线控制单元的5通道控制接口。