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组织脉冲微波消融过程中热声脉冲产生与传播的多物理场建模

Multi-physics modeling of thermoacoustic pulse generation and propagation during pulsed microwave ablation of tissue.

作者信息

Evans Audrey L, Ma Chu, Hagness Susan C

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5267-5271. doi: 10.1109/EMBC44109.2020.9175822.

DOI:10.1109/EMBC44109.2020.9175822
PMID:33019172
Abstract

Microwave-induced thermoacoustic (TA) imaging is a potential alternative to conventional real-time imaging methods for monitoring microwave ablation (MWA). In this study, we develop a multi-physics model for the generation and propagation of microwave-induced TA signals during pulsed MWA. Our model couples electromagnetics, heat transfer, and acoustics physics. We compare simulation and experimental results for a pulsed MWA system wherein a coaxial MWA antenna is used to heat water. The simulated and experimentally measured TA signals for this configuration are in good qualitative agreement. This multi-physics modeling tool is valuable for understanding the fundamentals of TA signal generation and propagation from within an evolving ablation zone.

摘要

微波诱导热声(TA)成像对于监测微波消融(MWA)而言,是一种有潜力替代传统实时成像方法的技术。在本研究中,我们针对脉冲式MWA期间微波诱导TA信号的产生与传播,开发了一个多物理场模型。我们的模型耦合了电磁学、热传导和声学物理。我们对一个使用同轴MWA天线加热水的脉冲MWA系统的模拟结果与实验结果进行了比较。此配置下模拟和实验测量得到的TA信号在定性上吻合良好。这种多物理场建模工具对于理解TA信号在不断演变的消融区内产生和传播的基本原理很有价值。

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