• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在数字时钟绘制测试中利用书写运动和潜伏期特征对认知障碍进行表型分析。

Phenotyping Cognitive Impairment using Graphomotor and Latency Features in Digital Clock Drawing Test.

作者信息

Davoudi Anis, Dion Catherine, Amini Shawna, Libon David J, Tighe Patrick J, Price Catherine C, Rashidi Parisa

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5657-5660. doi: 10.1109/EMBC44109.2020.9176469.

DOI:10.1109/EMBC44109.2020.9176469
PMID:33019260
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7594427/
Abstract

The Clock Drawing Test, where the participant is asked to draw a clock from memory and copy a model clock, is widely used for screening of cognitive impairment. The digital version of the clock test, the digital clock drawing test (dCDT), employs accelerometer and pressure sensors of a digital pen to capture time and pressure information from a participant's performance in a granular digital format. While visual features of the clock drawing test have previously been studied, little is known about the relationship between demographic and cognitive impairment characteristics with dCDT latency and graphomotor features. Here, we examine dCDT feature clusters with respect to sociodemographic and cognitive impairment outcomes. Our results show that the clusters are not significantly different in terms of age and gender, but did significantly differ in terms of education, Mini-Mental State Exam scores, and cognitive impairment diagnoses.This study shows that features extracted from digital clock drawings can provide important information regarding cognitive reserve and cognitive impairments.

摘要

时钟绘画测试要求参与者凭记忆画一个时钟并复制一个模型时钟,该测试被广泛用于认知障碍的筛查。时钟测试的数字版本,即数字时钟绘画测试(dCDT),利用数字笔的加速度计和压力传感器,以精细的数字格式从参与者的表现中获取时间和压力信息。虽然之前已经研究了时钟绘画测试的视觉特征,但对于人口统计学和认知障碍特征与dCDT潜伏期及书写运动特征之间的关系却知之甚少。在此,我们针对社会人口统计学和认知障碍结果来研究dCDT特征簇。我们的结果表明,这些特征簇在年龄和性别方面没有显著差异,但在教育程度、简易精神状态检查表得分和认知障碍诊断方面存在显著差异。这项研究表明,从数字时钟绘画中提取的特征可以提供有关认知储备和认知障碍的重要信息。

相似文献

1
Phenotyping Cognitive Impairment using Graphomotor and Latency Features in Digital Clock Drawing Test.在数字时钟绘制测试中利用书写运动和潜伏期特征对认知障碍进行表型分析。
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:5657-5660. doi: 10.1109/EMBC44109.2020.9176469.
2
Cognitive Correlates of Digital Clock Drawing Metrics in Older Adults with and without Mild Cognitive Impairment.认知相关的数字时钟绘制指标在老年人与轻度认知障碍。
J Alzheimers Dis. 2020;75(1):73-83. doi: 10.3233/JAD-191089.
3
Association Between the Digital Clock Drawing Test and Neuropsychological Test Performance: Large Community-Based Prospective Cohort (Framingham Heart Study).数字时钟绘画测试与神经心理学测试表现的关联:基于社区的大型前瞻性队列研究(弗雷明汉心脏研究)。
J Med Internet Res. 2021 Jun 8;23(6):e27407. doi: 10.2196/27407.
4
Machine Learning Analysis of Digital Clock Drawing Test Performance for Differential Classification of Mild Cognitive Impairment Subtypes Versus Alzheimer's Disease.机器学习分析数字时钟绘画测试表现,用于区分轻度认知障碍亚型与阿尔茨海默病。
J Int Neuropsychol Soc. 2020 Aug;26(7):690-700. doi: 10.1017/S1355617720000144. Epub 2020 Mar 23.
5
Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test.基于运动学、时间和视空间参数对非痴呆和阿尔茨海默病/血管性痴呆患者进行分类:数字钟画测试。
J Alzheimers Dis. 2021;82(1):47-57. doi: 10.3233/JAD-201129.
6
Diagnostic value of digital clock drawing test in comparison with CERAD neuropsychological battery total score for discrimination of patients in the early course of Alzheimer's disease from healthy individuals.数字时钟绘画测试与 CERAD 神经心理学成套测验总分在鉴别阿尔茨海默病早期患者与健康个体中的诊断价值比较。
Sci Rep. 2019 Mar 5;9(1):3543. doi: 10.1038/s41598-019-40010-0.
7
Clock Drawing Test and the diagnosis of amnestic mild cognitive impairment: can more detailed scoring systems do the work?画钟试验与遗忘型轻度认知障碍的诊断:更详细的评分系统能胜任这项工作吗?
J Clin Exp Neuropsychol. 2014;36(10):1076-83. doi: 10.1080/13803395.2014.977233. Epub 2014 Dec 8.
8
Digital clock drawing test metrics in older patients before and after endoscopy with sedation: An exploratory analysis.老年患者内镜镇静前后数字钟绘画测试指标:探索性分析。
Acta Anaesthesiol Scand. 2022 Feb;66(2):207-214. doi: 10.1111/aas.14003. Epub 2021 Nov 27.
9
Extended Application of Digital Clock Drawing Test in the Evaluation of Alzheimer's Disease Based on Artificial Intelligence and the Neural Basis.基于人工智能和神经基础的数字时钟绘画测试在阿尔茨海默病评估中的扩展应用。
Curr Alzheimer Res. 2021;18(14):1127-1139. doi: 10.2174/1567205018666211210150808.
10
Parkinson's Disease Cognitive Phenotypes Show Unique Clock Drawing Features when Measured with Digital Technology.帕金森病认知表型在使用数字技术测量时具有独特的时钟绘图特征。
J Parkinsons Dis. 2021;11(2):779-791. doi: 10.3233/JPD-202399.

引用本文的文献

1
Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations.AD-MCI和PD-MCI人群在数字时钟绘制测试中的认知功能差异。
Front Neurosci. 2025 Mar 13;19:1558448. doi: 10.3389/fnins.2025.1558448. eCollection 2025.
2
Conventional clock drawing tests have low to moderate reliability and validity for detecting subtle cognitive impairments in community-dwelling older adults.传统的画钟测试在检测社区居住的老年人细微认知障碍方面,可靠性和有效性较低至中等。
Front Aging Neurosci. 2023 Aug 29;15:1210585. doi: 10.3389/fnagi.2023.1210585. eCollection 2023.
3
The New Frontier of Perioperative Cognitive Medicine for Alzheimer's Disease and Related Dementias.

本文引用的文献

1
Cognitive Correlates of Digital Clock Drawing Metrics in Older Adults with and without Mild Cognitive Impairment.认知相关的数字时钟绘制指标在老年人与轻度认知障碍。
J Alzheimers Dis. 2020;75(1):73-83. doi: 10.3233/JAD-191089.
2
Feasibility and Rationale for Incorporating Frailty and Cognitive Screening Protocols in a Preoperative Anesthesia Clinic.将虚弱和认知筛查协议纳入术前麻醉诊所的可行性和基本原理。
Anesth Analg. 2019 Sep;129(3):830-838. doi: 10.1213/ANE.0000000000004190.
3
Diagnostic value of digital clock drawing test in comparison with CERAD neuropsychological battery total score for discrimination of patients in the early course of Alzheimer's disease from healthy individuals.
围手术期认知医学在阿尔茨海默病及相关痴呆中的新前沿。
Neurotherapeutics. 2022 Jan;19(1):132-142. doi: 10.1007/s13311-021-01180-w. Epub 2022 Jan 27.
4
Proof of concept: digital clock drawing behaviors prior to transcatheter aortic valve replacement may predict length of hospital stay and cost of care.概念验证:经导管主动脉瓣置换术前的数字时钟绘图行为可能预测住院时间和护理费用。
Explor Med. 2021;2:110-121. doi: 10.37349/emed.2021.00036. Epub 2021 Apr 30.
数字时钟绘画测试与 CERAD 神经心理学成套测验总分在鉴别阿尔茨海默病早期患者与健康个体中的诊断价值比较。
Sci Rep. 2019 Mar 5;9(1):3543. doi: 10.1038/s41598-019-40010-0.
4
Clock Drawing Performance Slows for Older Adults After Total Knee Replacement Surgery.全膝关节置换术后老年人的画钟测验表现变慢。
Anesth Analg. 2019 Jul;129(1):212-219. doi: 10.1213/ANE.0000000000003735.
5
THink: Inferring Cognitive Status from Subtle Behaviors.思考:从细微行为推断认知状态。
Proc AAAI Conf Artif Intell. 2014 Jul;2014:2898-2905.
6
Learning Classification Models of Cognitive Conditions from Subtle Behaviors in the Digital Clock Drawing Test.从数字时钟绘画测试中的细微行为学习认知状况的分类模型。
Mach Learn. 2016 Mar;102(3):393-441. doi: 10.1007/s10994-015-5529-5. Epub 2015 Oct 20.
7
Cognitive and connectome properties detectable through individual differences in graphomotor organization.通过书写运动组织的个体差异可检测到的认知和连接组特性。
Neuropsychologia. 2016 May;85:301-9. doi: 10.1016/j.neuropsychologia.2016.03.034. Epub 2016 Mar 30.
8
Preoperative Cognitive Stratification of Older Elective Surgical Patients: A Cross-Sectional Study.老年择期手术患者术前认知分层:一项横断面研究。
Anesth Analg. 2016 Jul;123(1):186-92. doi: 10.1213/ANE.0000000000001277.
9
Multiple imputation by chained equations: what is it and how does it work?多重链结方程插补法:是什么,以及它如何运作?
Int J Methods Psychiatr Res. 2011 Mar;20(1):40-9. doi: 10.1002/mpr.329.
10
The Mini-Mental State Examination (MMSE).简易精神状态检查表(MMSE)。
J Gerontol Nurs. 1999 May;25(5):8-9. doi: 10.3928/0098-9134-19990501-08.