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升主动脉瘤和保留主动脉瓣的主动脉根部置换术:来自波兰单一中心的长期结果。

Aneurysm of the aortic root and valve‑sparing aortic root replacement: long-term outcomes from a single Polish center.

出版信息

Kardiol Pol. 2020 Dec 23;78(12):1235-1242. doi: 10.33963/KP.15636. Epub 2020 Oct 5.

Abstract

BACKGROUND

Valve-sparing aortic root replacement (VSARR) techniques are an alternative to the classic Bentall procedure when aortic root aneurysm is not accompanied by aortic valve stenosis, and the regurgitant aortic valve is amenable to repair.

AIMS

The aim of the study was to assess long -term outcomes of valve sparing aortic root replacement using the David technique and the Yacoub technique.

METHODS

A total of 101 consecutive, elective VSARR procedures were performed from January 2010 to April 2020 including 52 David procedures (51.5%) and 49 Yacoub procedures (48.5%). We analyzed mortality, freedom from reoperation, and freedom from aortic valve regurgitation. The analysis was performed for the entire study cohort and for 2 subgroups: the David technique and the Yacoub technique.

RESULTS

The mean (SD) age was 50.2 (16.1) years; 90 (89.1%) patients were male. The median (interquartile range [IQR]) EuroScore II was 3.7 (2.7‒5.8). At 1, 5, and 8 years after surgery, survival (SE) was 98% (3%), 91.8% (8%), and 91.8% (8%), respectively, whereas freedom from reoperation (SE) was 100%, 97% (3%), and 97% (3%), respectively. Follow‑up echocardiography performed at a median (IQR) of 18.7 (2.5‒36.7) months postsurgery revealed freedom from aortic valve regurgitation in 90.8% of patients. No significant differences in mortality, freedom from reoperation, and freedom from aortic valve regurgitation were noted between the David and Yacoub subgroups.

CONCLUSIONS

VSARR is a safe and effective surgical technique in patients with aortic root aneurysm, as the associated mortality, reoperation rate, and aortic valve regurgitation recurrence are low.

摘要

背景

当主动脉根部瘤不伴有主动脉瓣狭窄且反流的主动脉瓣可修复时,保留瓣膜的主动脉根部替换(VSARR)技术是经典 Bentall 手术的替代方法。

目的

本研究旨在评估使用 David 技术和 Yacoub 技术进行保留瓣膜的主动脉根部替换的长期结果。

方法

2010 年 1 月至 2020 年 4 月,连续 101 例选择性 VSARR 手术,包括 52 例 David 手术(51.5%)和 49 例 Yacoub 手术(48.5%)。我们分析了死亡率、免于再次手术和免于主动脉瓣反流。分析了整个研究队列和 2 个亚组(David 技术和 Yacoub 技术)的死亡率、免于再次手术和免于主动脉瓣反流。

结果

平均(SD)年龄为 50.2(16.1)岁;90 例(89.1%)为男性。中位数(四分位距[IQR])EuroScore II 为 3.7(2.7-5.8)。手术后 1、5 和 8 年,生存率(SE)分别为 98%(3%)、91.8%(8%)和 91.8%(8%),而免于再次手术的生存率(SE)分别为 100%、97%(3%)和 97%(3%)。术后中位数(IQR)为 18.7(2.5-36.7)个月的随访超声心动图显示,90.8%的患者无主动脉瓣反流。David 和 Yacoub 亚组之间的死亡率、免于再次手术和免于主动脉瓣反流无显著差异。

结论

在主动脉根部瘤患者中,VSARR 是一种安全有效的手术技术,因为其相关死亡率、再次手术率和主动脉瓣反流复发率较低。

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