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1
Challenging the evidence for hepoxilin A being a mediator of neutrophil epithelial transmigration.质疑肝氧合素A作为中性粒细胞上皮迁移介质的证据。
Am J Physiol Lung Cell Mol Physiol. 2020 Oct 1;319(4):L752-L753. doi: 10.1152/ajplung.00349.2020.
2
Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers.海帕西啶 A（3）促进表达脂氧合酶的气道上皮屏障中嗜中性粒细胞的突破。
J Immunol. 2012 Nov 15;189(10):4960-9. doi: 10.4049/jimmunol.1201922. Epub 2012 Oct 8.
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A lipid mediator hepoxilin A3 is a natural inducer of neutrophil extracellular traps in human neutrophils.脂质介质hepoxilin A3是人类中性粒细胞中中性粒细胞胞外陷阱的天然诱导剂。
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Multidrug resistance-associated transporter 2 regulates mucosal inflammation by facilitating the synthesis of hepoxilin A3.多药耐药相关转运蛋白2通过促进肝氧素A3的合成来调节黏膜炎症。
J Immunol. 2008 Dec 1;181(11):8044-52. doi: 10.4049/jimmunol.181.11.8044.
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Chemical synthesis and actions of 11,12-thiirano-hepoxilin A3.11,12-环氧硫杂二十碳三烯酸A3的化学合成与作用
J Lipid Mediat Cell Signal. 1996 Jan;13(1):63-72. doi: 10.1016/0929-7855(95)00045-3.
6
Receptor-mediated action of hepoxilin A3 releases diacylglycerol and arachidonic acid from human neutrophils.肝氧前列醇A3的受体介导作用从人中性粒细胞中释放二酰甘油和花生四烯酸。
Biochem Biophys Res Commun. 1990 Sep 28;171(3):944-8. doi: 10.1016/0006-291x(90)90775-i.
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Bacterial-induced hepoxilin A3 secretion as a pro-inflammatory mediator.细菌诱导的肝氧素A3作为促炎介质的分泌
FEBS J. 2007 Jul;274(14):3513-3518. doi: 10.1111/j.1742-4658.2007.05911.x. Epub 2007 Jul 2.
8
Hepoxilin A3 induces heat shock protein (HSP72) expression in human neutrophils.肝氧素A3诱导人中性粒细胞中热休克蛋白（HSP72）的表达。
Biochem Biophys Res Commun. 1991 Aug 30;179(1):52-6. doi: 10.1016/0006-291x(91)91332-7.
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Hepoxilin-evoked intracellular reorganization of calcium in human neutrophils: a confocal microscopy study.人中性粒细胞中 hepoxilin 引发的细胞内钙重组：共聚焦显微镜研究
Exp Cell Res. 1997 Feb 1;230(2):337-41. doi: 10.1006/excr.1996.3425.
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Hepoxilin A3 inhibits agonist-evoked rise in free intracellular calcium in human neutrophils.肝氧素A3抑制激动剂诱发的人中性粒细胞内游离钙升高。
Adv Exp Med Biol. 1997;400A:375-80. doi: 10.1007/978-1-4615-5325-0_50.

本文引用的文献

1
Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration during Infection.肺炎球菌溶血素诱导感染期间 12-脂氧合酶依赖的中性粒细胞迁移。
J Immunol. 2020 Jan 1;204(1):101-111. doi: 10.4049/jimmunol.1800748. Epub 2019 Nov 27.
2
Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis.肠 P 糖蛋白将内源性大麻素输出到细胞外以防止炎症和维持体内平衡。
J Clin Invest. 2018 Aug 31;128(9):4044-4056. doi: 10.1172/JCI96817. Epub 2018 Aug 13.
3
Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis.解析脂氧合酶在铁死亡起始和执行过程中的作用
ACS Cent Sci. 2018 Mar 28;4(3):387-396. doi: 10.1021/acscentsci.7b00589. Epub 2018 Feb 7.
4
Neutrophil-Derived Cytosolic PLA2α Contributes to Bacterial-Induced Neutrophil Transepithelial Migration.中性粒细胞衍生的胞质型磷脂酶A2α促进细菌诱导的中性粒细胞跨上皮迁移。
J Immunol. 2017 Oct 15;199(8):2873-2884. doi: 10.4049/jimmunol.1700539. Epub 2017 Sep 8.
5
Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration.肝氧素A3和白三烯B4的不同细胞来源被用于协调细菌诱导的中性粒细胞跨上皮迁移。
J Immunol. 2015 Feb 1;194(3):1304-15. doi: 10.4049/jimmunol.1402489. Epub 2014 Dec 29.
6
Pathogen induced chemo-attractant hepoxilin A3 drives neutrophils, but not eosinophils across epithelial barriers.病原体诱导的趋化因子 hepoxilin A3 驱动中性粒细胞，而不是嗜酸性粒细胞穿过上皮屏障。
Prostaglandins Other Lipid Mediat. 2014 Jan;108:1-8. doi: 10.1016/j.prostaglandins.2013.11.001. Epub 2013 Dec 4.
7
Systemic disease during Streptococcus pneumoniae acute lung infection requires 12-lipoxygenase-dependent inflammation.肺炎链球菌急性肺部感染期间的系统性疾病需要 12-脂氧合酶依赖性炎症。
J Immunol. 2013 Nov 15;191(10):5115-23. doi: 10.4049/jimmunol.1300522. Epub 2013 Oct 2.
8
Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers.海帕西啶 A（3）促进表达脂氧合酶的气道上皮屏障中嗜中性粒细胞的突破。
J Immunol. 2012 Nov 15;189(10):4960-9. doi: 10.4049/jimmunol.1201922. Epub 2012 Oct 8.
9
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate is a potent inhibitor of 5-lipoxygenase.肉桂酰基-3,4-二羟基-α-氰基肉桂酸酯是 5-脂氧合酶的强效抑制剂。
J Pharmacol Exp Ther. 2011 Jul;338(1):205-13. doi: 10.1124/jpet.111.180794. Epub 2011 Mar 29.
10
Selective eicosanoid-generating capacity of cytoplasmic phospholipase A2 in Pseudomonas aeruginosa-infected epithelial cells.铜绿假单胞菌感染上皮细胞中细胞质磷脂酶 A2 的选择性花生四烯酸生成能力。
Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L286-94. doi: 10.1152/ajplung.00147.2010. Epub 2010 Nov 19.

Challenging the evidence for hepoxilin A being a mediator of neutrophil epithelial transmigration.

作者信息

Brash Alan R

机构信息

Division of Clinical Pharmacology, Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee.

出版信息

Am J Physiol Lung Cell Mol Physiol. 2020 Oct 1;319(4):L752-L753. doi: 10.1152/ajplung.00349.2020.

DOI:10.1152/ajplung.00349.2020
PMID:33021845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7642896/
Abstract
摘要