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新型冠状病毒肺炎相关高凝状态的预防与治疗:阿尔及利亚输血与血液生物学学会的建议

Prevention and treatment of COVID-19-associated hypercoagulability: Recommendations of the Algerian society of transfusion and hemobiology.

作者信息

Chekkal M, Deba T, Hadjali S, Lamara H, Oulaa H, Zouai K, Hariti G

机构信息

Service d'hémobiologie et banque de sang, EHU d'Oran, Oran, Algeria.

Service d'hémobiologie et banque de sang, EHU d'Oran, Oran, Algeria.

出版信息

Transfus Clin Biol. 2020 Nov;27(4):203-206. doi: 10.1016/j.tracli.2020.09.004. Epub 2020 Oct 3.

Abstract

Since December 2019, an outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, has spread throughout the world. Coagulation dysfunction is one of the major causes of death in patients with severe COVID-19. Several recent observations in Algeria and elsewhere maintain that a pulmonary embolism is frequent in patients with COVID-19 with a high incidence in intensive care. In addition, other studies have shown that many deceased patients have diagnostic criteria for disseminated intravascular coagulation (DIC) set by the International society of hemostasis and thrombosis (ISTH). The office of the Algerian society of transfusion and hemobiology composed of hemostasis and blood transfusion experts from Algerian hospitals on the epidemic front line have established a consensus on the issue through 4 axes: Indication of thromboprophylaxis, monitoring of hemostasis, indications of transfusion in the event of disseminated intravascular coagulation (DIC) and anticoagulant treatment after discharge.

摘要

自2019年12月以来,中国武汉爆发的2019冠状病毒病(COVID-19)已蔓延至全球。凝血功能障碍是重症COVID-19患者的主要死亡原因之一。最近在阿尔及利亚和其他地方的一些观察结果表明,COVID-19患者中肺栓塞很常见,在重症监护中发病率很高。此外,其他研究表明,许多死亡患者符合国际止血与血栓学会(ISTH)制定的弥散性血管内凝血(DIC)诊断标准。由来自阿尔及利亚疫情前线医院的止血和输血专家组成的阿尔及利亚输血与血液生物学协会办公室,已通过四个方面就该问题达成了共识:血栓预防指征、止血监测、弥散性血管内凝血(DIC)时的输血指征以及出院后的抗凝治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e8c/7532757/6106a61176aa/gr1_lrg.jpg

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