Firestone R A, Pisano J M, Garrity G M, Fromtling R A, Zimmerman S B
J Med Chem. 1987 Aug;30(8):1519-21. doi: 10.1021/jm00391a043.
Lysosomotropic detergents, which kill mammalian cells by disrupting lysosomal membranes, have now been found to be antifungals also. All strains in our assay are susceptible. The mode of action is as yet undetermined, but intracellular vacuoles may be the primary targets.
溶酶体亲和性去污剂通过破坏溶酶体膜来杀死哺乳动物细胞，现在发现它也具有抗真菌作用。我们试验中的所有菌株都对此敏感。其作用方式尚未确定，但细胞内液泡可能是主要靶点。
