UCL Institute of Education, Centre for Longitudinal Studies, London, UK
UCL Institute of Education, Cohort and Longitudinal Studies Enhancement Resources, London, UK.
J Epidemiol Community Health. 2021 Feb;75(2):193-196. doi: 10.1136/jech-2020-214423. Epub 2020 Oct 6.
Disadvantaged socioeconomic position (SEP) in early and adult life has been repeatedly associated with premature mortality. However, it is unclear whether these inequalities differ across time, nor if they are consistent across different SEP indicators.
British birth cohorts born in 1946, 1958 and 1970 were used, and multiple SEP indicators in early and adult life were examined. Deaths were identified via national statistics or notifications. Cox proportional hazard models were used to estimate associations between ridit scored SEP indicators and all-cause mortality risk-from 26 to 43 years (n=40 784), 26 to 58 years (n=35 431) and 26 to 70 years (n=5353).
More disadvantaged SEP was associated with higher mortality risk-magnitudes of association were similar across cohort and each SEP indicator. For example, HRs (95% CI) from 26 to 43 years comparing lowest to highest paternal social class were 2.74 (1.02 to 7.32) in 1946c, 1.66 (1.03 to 2.69) in 1958c, and 1.94 (1.20 to 3.15) in 1970c. Paternal social class, adult social class and housing tenure were each independently associated with mortality risk.
Socioeconomic circumstances in early and adult life show persisting associations with premature mortality from 1971 to 2016, reaffirming the need to address socioeconomic factors across life to reduce inequalities in survival to older age.
早期和成年时期处于不利的社会经济地位(SEP)与过早死亡反复相关。然而,目前尚不清楚这些不平等是否会随时间而变化,也不清楚它们是否在不同的 SEP 指标之间具有一致性。
本研究使用了英国分别出生于 1946 年、1958 年和 1970 年的队列,研究了早期和成年时期的多个 SEP 指标。通过国家统计数据或通知来确定死亡情况。使用 Cox 比例风险模型来估计评分 SEP 指标与全因死亡率风险之间的关联——从 26 岁到 43 岁(n=40784)、26 岁到 58 岁(n=35431)和 26 岁到 70 岁(n=5353)。
处于更不利 SEP 的人具有更高的死亡风险——关联的幅度在各队列和每个 SEP 指标中均相似。例如,1946c 队列中,最低与最高父亲社会阶层相比,26 岁到 43 岁的 HR(95%CI)为 2.74(1.02 至 7.32),1958c 队列为 1.66(1.03 至 2.69),1970c 队列为 1.94(1.20 至 3.15)。父亲的社会阶层、成年时的社会阶层和住房所有权均与死亡风险独立相关。
从 1971 年到 2016 年,早期和成年时期的社会经济状况与过早死亡持续相关,这再次证实了需要在整个生命周期中解决社会经济因素,以减少生存到老年的不平等。