Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche "Togo Rosati", via G. Salvemini, 1, 06126, Perugia, Italy.
Arch Virol. 2020 Dec;165(12):3007-3009. doi: 10.1007/s00705-020-04836-8. Epub 2020 Oct 6.
To gain further insight into the genomic features of border disease virus (BDV), we determined the nearly complete genome sequence of isolate TO/121/04 from an aborted ovine fetus. Its genome contains a single open reading frame (ORF), which comprises 11,681 nucleotides encoding a polyprotein of 3893 amino acids. Phylogenetic analysis of the near full-length genome sequence showed that the BDV isolate differed significantly from all ovine pestiviruses identified so far, thus re-affirming the presence in Italy of this novel genetic group, termed BDV-7.
为了更深入地了解边境病病毒（BDV）的基因组特征，我们测定了来自一只流产绵羊胎儿的 TO/121/04 分离株的近全长基因组序列。该基因组包含一个单一的开放阅读框（ORF），编码一个 3893 个氨基酸的多蛋白。对近全长基因组序列的系统进化分析表明，BDV 分离株与迄今为止鉴定的所有绵羊瘟病毒有显著差异，从而再次证实意大利存在这种新型的遗传群，称为 BDV-7。
