Mat Olivier, Gankam Fabrice, Goubella Ahmed, Colombie Vincent, Blecic Serge, Mat Quentin, Philippart Patrick
Department of Nephrology, EpiCURA, Ath, Belgium.
Department of Infectious Diseases, EpiCURA, Ath, Belgium.
Perit Dial Int. 2021 May;41(3):337-340. doi: 10.1177/0896860820962934. Epub 2020 Oct 7.
Infections with (LM) are very uncommon and severe especially in immunocompromised people. We report a continuous cycling peritoneal dialysis (CCPD) patient who presented initially disseminated listeriosis with peritonitis. He was successfully treated with intraperitoneal and intravenous ampicillin but died unfortunately from a cardiorespiratory arrest due to food inhalation. It is the 20th case of such peritonitis mentioned among PD patients and the first reported in Belgium. This case illustrates the importance of a systematic approach to get quick diagnosis and effective antibiotic readjustment. Empiric therapy is not effective on Listeria which is naturally resistant to cephalosporins and poorly sensitive to vancomycin. Ampicillin is the first-line antibiotic. In case of penicillin allergy, trimethoprim-sulfamethoxazole or erythromycin can be used successfully. Identification of LM serotype has a prognostic value. PD educative programmes should recommend to avoid unpasteurized dairy products to prevent listeriosis.
单核细胞增生李斯特菌（LM）感染非常罕见且严重，尤其是在免疫功能低下的人群中。我们报告了一名持续循环腹膜透析（CCPD）患者，该患者最初表现为播散性李斯特菌病并伴有腹膜炎。他接受了腹腔内和静脉注射氨苄西林治疗，治疗成功，但不幸的是因食物吸入导致心肺骤停而死亡。这是腹膜透析患者中提到的第20例此类腹膜炎病例，也是比利时首次报道的病例。该病例说明了采用系统方法进行快速诊断和有效抗生素调整的重要性。经验性治疗对李斯特菌无效，因为李斯特菌天然对头孢菌素耐药，对万古霉素敏感性较差。氨苄西林是一线抗生素。如果对青霉素过敏，可以成功使用复方新诺明或红霉素。鉴定LM血清型具有预后价值。腹膜透析教育计划应建议避免食用未经巴氏消毒的乳制品以预防李斯特菌病。
