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基于短信干预对人类免疫缺陷病毒患者的经济与流行病学评估。

Economic and epidemiological evaluation of text message-based interventions in patients with the Human Immunodeficiency Virus.

作者信息

Santos Wendel Mombaque Dos, Primeira Marcelo Ribeiro, Paiva Larissa Garcia de, Padoin Stela Maris de Mello

机构信息

Empresa Brasileira de Serviços Hospitalares, Hospital Universitário de Santa Maria, Santa Maria, RS, Brazil.

Universidade Federal de Santa Maria, Departamento de Enfermagem, Santa Maria, RS, Brazil.

出版信息

Rev Lat Am Enfermagem. 2020 Sep 22;28:e3365. doi: 10.1590/1518-8345.3614.3365. eCollection 2020.

Abstract

OBJECTIVE

to evaluate the cost-effectiveness ratio and the budget impact of sending text messages associated with medical consultations in order to reduce the viral load of patients infected with the Human Immunodeficiency Virus.

METHOD

a randomized clinical trial, basis for the development of a dynamic cohort model with Markov states in order to compare medical appointments for adults infected with the Human Immunodeficiency Virus versus the alternative strategy that associated medical consultations to sending text messages through telephone.

RESULTS

156 adults participated in the study. As for the viral load, it was verified that in the control group there was an increase, in the intervention group A (weekly messages) there was a reduction (p = 0.002) and in group B (biweekly messages) there was no statistically significant difference. Sending text messages would prevent 286,538 new infections by the Human Immunodeficiency Virus and 282 deaths in the 20-year period, compared to the standard treatment. The alternative strategy would result in saving R$ 14 billion in treatment costs.

CONCLUSION

weekly sending messages in association with the standard treatment can reduce the circulating viral load due to its effect in decreasing new infections, in addition to reducing health costs.

摘要

目的

评估与医疗咨询相关的短信发送的成本效益比及预算影响,以降低感染人类免疫缺陷病毒患者的病毒载量。

方法

一项随机临床试验,作为开发具有马尔可夫状态的动态队列模型的基础,以便比较感染人类免疫缺陷病毒的成年人的医疗预约与通过电话发送短信相关医疗咨询的替代策略。

结果

156名成年人参与了该研究。关于病毒载量,证实对照组有所增加,干预组A(每周发送短信)有所降低(p = 0.002),而组B(每两周发送短信)无统计学显著差异。与标准治疗相比,发送短信在20年内可预防286,538例人类免疫缺陷病毒新感染和282例死亡。替代策略将节省140亿雷亚尔的治疗成本。

结论

除了降低医疗成本外,每周与标准治疗相关联发送短信可因其减少新感染的作用而降低循环病毒载量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ea0/7529449/74b5cfde1c86/0104-1169-rlae-28-e3365-gf01.jpg

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