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通过静脉数字减影血管造影术检测未破裂的家族性颅内动脉瘤。对两个患病家族进行筛查。

Detection of unruptured familial intracranial aneurysms by intravenous digital subtraction angiography. Screening of two affected families.

作者信息

ter Berg J W, Overtoom T M, Ludwig J W, Bijlsma J B, Tulleken C A, Willemse J

出版信息

Neuroradiology. 1987;29(3):272-6. doi: 10.1007/BF00451766.

Abstract

The authors discuss the detection of intracranial aneurysms (IA) by means of intravenous digital angiography (ivDSA) in (a)symptomatic first degree relatives of families in which two or more individuals have IA. ivDSA is an almost noninvasive and low-risk diagnostic procedure. Screening, by means of ivDSA, of two affected families is described. In family I which includes 7 members with proven IA, ivDSA has been carried out in 36 asymptomatic individuals: in one, a 6 X 15 mm aneurysm was found at the left posterior communicating artery (PCoA). In family II, including one member with a proven IA and another with a subarachnoid hemorrhage, ivDSA has been carried out in 4 members: one aneurysm with a diameter of 6 mm was found at the left PCoA. Conventional cerebral angiography (CCA) confirmed both IA's. Neurosurgical treatment followed. The advantages and disadvantages of ivDSA vs. CCA as elective screening procedure in such cases are discussed. Screening of asymptomatic first degree relatives of cases with familial IA by means of ivDSA is strongly advocated.

摘要

作者讨论了通过静脉数字血管造影(ivDSA)对两个或更多个体患有颅内动脉瘤(IA)的家族中(有)症状的一级亲属进行颅内动脉瘤检测的情况。ivDSA是一种几乎无创且低风险的诊断程序。描述了通过ivDSA对两个患病家族进行的筛查。在家族I中,有7名成员被证实患有IA,对36名无症状个体进行了ivDSA检查:其中1人在左后交通动脉(PCoA)发现一个6×15mm的动脉瘤。在家族II中,包括1名被证实患有IA的成员和另一名患有蛛网膜下腔出血的成员,对4名成员进行了ivDSA检查:在左PCoA发现一个直径6mm的动脉瘤。传统脑血管造影(CCA)证实了这两个IA。随后进行了神经外科治疗。讨论了在这种情况下,ivDSA与CCA作为选择性筛查程序的优缺点。强烈主张通过ivDSA对家族性IA病例的无症状一级亲属进行筛查。

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