Derriennic M, Reynaud A, Launay C, Courtieu A L
Pathol Biol (Paris). 1987 May;35(5):572-6.
The in vitro activities of amoxicillin, amoxicillin-clavulanic acid, piperacillin, cefoxitin, cefotetan, cefotaxime, cefmenoxime, ceftizoxime, latamoxef, clindamycin and metronidazole, were determined by agar dilution method for 196 clinical isolates of anaerobic bacteria. No metronidazole resistant strains could be found, 10% of tested strains were resistant to clindamycin. The majority of these strains was susceptible to amoxicillin-clavulanic acid and piperacillin; less than 10% were resistant to latamoxef, cefoxitin, cefotaxime and ceftizoxime; whereas 15 to 20% were resistant to amoxicillin, cefotetan and cefmenoxime.
采用琼脂稀释法测定了阿莫西林、阿莫西林-克拉维酸、哌拉西林、头孢西丁、头孢替坦、头孢噻肟、头孢甲肟、头孢唑肟、拉氧头孢、克林霉素和甲硝唑对196株临床分离厌氧菌的体外活性。未发现对甲硝唑耐药的菌株，10%的受试菌株对克林霉素耐药。这些菌株中的大多数对阿莫西林-克拉维酸和哌拉西林敏感；对拉氧头孢、头孢西丁、头孢噻肟和头孢唑肟耐药的菌株不到10%；而对阿莫西林、头孢替坦和头孢甲肟耐药的菌株为15%至20%。
